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Diethyl 2,3-bis(acetyloxy)butanedioate, also known as diethyl succinate diacetate, is a chemical compound with the molecular formula C10H14O8. It is a colorless, viscous liquid that is soluble in water and most organic solvents. diethyl 2,3-bis(acetyloxy)butanedioate is an ester derivative of succinic acid, where two hydroxyl groups are replaced by acetyloxy groups, and the remaining two hydroxyl groups are esterified with ethanol. Diethyl 2,3-bis(acetyloxy)butanedioate is primarily used as an intermediate in the synthesis of various chemicals, including pharmaceuticals, agrochemicals, and other specialty chemicals. It is also used as a solvent and a plasticizer. Due to its versatile chemical structure, it plays a significant role in the chemical industry, contributing to the production of a wide range of products.

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  • 2364-65-0 Structure
  • Basic information

    1. Product Name: diethyl 2,3-bis(acetyloxy)butanedioate
    2. Synonyms: butanedioic acid, 2,3-bis(acetyloxy)-, diethyl ester; Diethyl 2,3-diacetoxysuccinate
    3. CAS NO:2364-65-0
    4. Molecular Formula: C12H18O8
    5. Molecular Weight: 290.2665
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2364-65-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 295.999°C at 760 mmHg
    3. Flash Point: 133.514°C
    4. Appearance: N/A
    5. Density: 1.203g/cm3
    6. Vapor Pressure: 0.001mmHg at 25°C
    7. Refractive Index: 1.449
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: diethyl 2,3-bis(acetyloxy)butanedioate(CAS DataBase Reference)
    11. NIST Chemistry Reference: diethyl 2,3-bis(acetyloxy)butanedioate(2364-65-0)
    12. EPA Substance Registry System: diethyl 2,3-bis(acetyloxy)butanedioate(2364-65-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2364-65-0(Hazardous Substances Data)

2364-65-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2364-65-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,6 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2364-65:
(6*2)+(5*3)+(4*6)+(3*4)+(2*6)+(1*5)=80
80 % 10 = 0
So 2364-65-0 is a valid CAS Registry Number.

2364-65-0Relevant articles and documents

Preparation method of 2-amino-5-bromopyridine

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Paragraph 0016; 0031-0037, (2020/05/05)

The invention belongs to the technical field of organic synthesis, and specifically relates to a preparation method of 2-amino-5-bromopyridine. The method comprises the following steps: 2-aminopyridine serves as a raw material, dichloromethane or trichloromethane serves as a solvent, 2-aminopyridine and phenyl trimethyl ammonium tribromide carry out reactions for 1-3 hours at the temperature of 20-50 DEG C, and the molar ratio of 2-aminopyridine to phenyl trimethyl ammonium tribromide is 0.7-1.4. The preparation method provided by the invention has the beneficial effects that (1) the generation of a large number of 3-position byproducts in a traditional preparation method is avoided, and the waste of raw materials and the load of subsequent separation are reduced; and (2) the raw materialnamely 2-aminopyridine is easy to obtain and low in cost, the synthesis route has the advantages of high yield and mild conditions, no 3-position byproduct is generated in the whole process, and the preparation method has an industrialization prospect.

Novel preparation method D-(-)- tartaric acid

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Paragraph 0016; 0031-0037, (2020/05/05)

The invention discloses a new preparation method for D-(-)-tartaric acid, and relates to the preparation method of the resolving agent D-(-)-tartaric acid widely applied in the field of pharmaceuticalsynthesis. The method includes the following steps successively: taking (2R,3R)-2,3-diethyl dihydroxy succinate as a raw material, after hydroxyl protection, substituting with an acetoxyl group, andfinally, carrying out hydrolysis reaction to obtain D-(-)-tartaric acid. The invention provides a new route comprising the steps of directly preparing chiral hydroxyl protected D-(-)-tartaric acid through the selective substitution reaction and then hydrolyzing to obtain the product. The reaction conditions of all the steps are easy to operate, the process is simple, and the reaction of each stepis conventional to operate.

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