2364-65-0

Basic information

• Product Name: diethyl 2,3-bis(acetyloxy)butanedioate
• Synonyms: butanedioic acid, 2,3-bis(acetyloxy)-, diethyl ester; Diethyl 2,3-diacetoxysuccinate
• CAS NO: 2364-65-0
• Molecular Formula: C₁₂H₁₈O₈
• Molecular Weight: 290.2665
• Mol File: 2364-65-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 295.999°C at 760 mmHg
• Flash Point: 133.514°C
• Density: 1.203g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.449
• CAS DataBase Reference: diethyl 2,3-bis(acetyloxy)butanedioate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2,3-bis(acetyloxy)butanedioate(2364-65-0)
• EPA Substance Registry System: diethyl 2,3-bis(acetyloxy)butanedioate(2364-65-0)

Safety Data

• Hazardous Substances Data: 2364-65-0(Hazardous Substances Data)

Upstream product

• 64-19-7 acetic acid 
• 57968-71-5 (+/-)-diethyl tartrate 
• 75-36-5 acetyl chloride 
• 408332-88-7 Diethyl tartrate 
• 98559-16-1 (R)-hydroxy-oxalacetic acid diethyl ester 
• 108-24-7 acetic anhydride 

Downstream Products

• 147-71-7 D-tartaric acid 
• 10024-90-5 4-methoxy-3-methylacetophenone 

Relevant articles and documents

Preparation method of 2-amino-5-bromopyridine

The invention belongs to the technical field of organic synthesis, and specifically relates to a preparation method of 2-amino-5-bromopyridine. The method comprises the following steps: 2-aminopyridine serves as a raw material, dichloromethane or trichloromethane serves as a solvent, 2-aminopyridine and phenyl trimethyl ammonium tribromide carry out reactions for 1-3 hours at the temperature of 20-50 DEG C, and the molar ratio of 2-aminopyridine to phenyl trimethyl ammonium tribromide is 0.7-1.4. The preparation method provided by the invention has the beneficial effects that (1) the generation of a large number of 3-position byproducts in a traditional preparation method is avoided, and the waste of raw materials and the load of subsequent separation are reduced; and (2) the raw materialnamely 2-aminopyridine is easy to obtain and low in cost, the synthesis route has the advantages of high yield and mild conditions, no 3-position byproduct is generated in the whole process, and the preparation method has an industrialization prospect.