23693-97-2Relevant academic research and scientific papers
Solvent free synthesis of 2-acylpyrroles and its derivatives catalysed by reuseable zinc oxide
Zhang, Shuguang,Feng, Chengliang,Cai, Jin,Chen, Junqing,Hu, Huayou,Ji, Min
, p. 480 - 482 (2013/09/12)
A highly efficient procedure for preparing 2-acylpyrroles and its derivatives is described. The products were obtained through regioselective Friedel-Crafts reactions of pyrroles and its derivatives with alkyl or aryl acid chlorides catalysed by zinc oxide under solvent-free conditions. This method has the advantages of green chemistry, operational simplicity, solvent-free conditions, and recoverable catalyst.
Selective α-Chlorination of Acetylpyrroles
Croce, Piero Dalla,Ferraccioli, Rafaella,Ritieni, Alberto
, p. 212 - 213 (2007/10/02)
Reaction of acetylpyrroles with benzyltrimethylammonium dichloroiodate in tetrahydrofuran solution leads to the corresponding α-chloro derivatives with high selectivity and good yields.
Direct Vilsmeier-Haack Chloroacetylation of Pyrroles
Croce, Piero Dalla,Rosa, Concetta La,Ritieni, Alberto
, p. 783 - 784 (2007/10/02)
Reaction of pyrroles with N,N-dimethyl-2-chloroacetamide in the presence of phosphorus oxychloride leads to a mixture of 2- and 3-chloroacetylpyrroles, which can be separated by chromatography.
