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Usage

Uses

Used in Pharmaceutical Industry:
2-(4-Bromophenylamino)acetohydrazide is used as a building block for the preparation of various biologically active compounds, such as pharmaceuticals. Its unique structure allows it to interact with biological molecules, making it a promising candidate for medicinal chemistry.
Used in Agrochemical Industry:
2-(4-Bromophenylamino)acetohydrazide is also used in the synthesis of agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used in Chemical Biology:
Due to its ability to interact with biological molecules, 2-(4-Bromophenylamino)acetohydrazide has potential applications in chemical biology, where it can be utilized in the study and manipulation of biological systems.
Used as a Reagent in Chemical Reactions:
2-(4-Bromophenylamino)acetohydrazide may serve as a reagent in various chemical reactions, facilitating the synthesis of complex organic compounds and contributing to the advancement of organic chemistry.
Used as a Starting Material for Organic Synthesis:
As a hydrazide derivative with a bromo-substituted phenyl ring, 2-(4-Bromophenylamino)acetohydrazide is a valuable starting material for the synthesis of a wide range of organic compounds, further expanding its utility in the field of chemistry.

InChI:InChI=1/C8H10BrN3O/c9-6-1-3-7(4-2-6)11-5-8(13)12-10/h1-4,11H,5,10H2,(H,12,13)

Upstream product

• 2521-92-8 ethyl 2-((4-bromophenyl)amino)acetate 
• 213995-52-9 2-(4-bromophenylamino)acetamide 
• 106-40-1 4-bromo-aniline 
• 13370-62-2 N‐(4-bromophenyl)glycine 

Downstream Products

• 1384182-82-4 ethyl 2-(2-(2-(4-bromophenylamino)acetyl)hydrazono)propanoate 
• 882760-34-1 2-(4-bromophenylamino)-N'-(1-phenylethylidene)acetohydrazide 
• 1353648-15-3 2-(4-bromophenylamino)-N'-(propan-2-ylidene)acetohydrazide 
• 882760-26-1 2-(4-bromophenylamino)-N'-(2-chlorobenzylidene)acetohydrazide 
• 325971-85-5 2-(4-bromophenylamino)-N'-(2-hydroxybenzylidene)acetohydrazide 
• 325971-79-7 2-(4-bromophenylamino)-N'-(4-nitrobenzylidene)acetohydrazide 
• 1353648-14-2 2-(4-bromophenylamino)-N'-(2-nitrobenzylidene)acetohydrazide 
• 92516-01-3 C₁₅H₁₅BrN₄OS 

Relevant academic research and scientific papers

Transition metal complexes of novel ethyl pyruvate hydrazones as potential antitumor agents: Synthesis and physicochemical properties, DNA interactions and antiproliferative activity

A new series of ethyl pyruvate hydrazones and their later first row transition metal(II) complexes have been synthesized and characterized by means of elemental analyses, vibrational, electronic, 1H and 13C NMR, electron paramagnetic resonance, and mass spectroscopic techniques along with thermal and magnetic studies. All complexes were found to be monomeric in nature and have octahedral geometry. The prepared compounds were evaluated for antiproliferative activity against the two human cancer cell lines (HeLa and HepG2). The Cu(II) complexes were found to have potential activity against the cell lines used than the ligand and other complexes. In addition, the DNA-binding/cleaving capacity of the compounds were analyzed by absorption spectroscopy, viscosity measurement, thermal denaturation studies and gel electrophoresis methods.

Synthesis and evaluation of some novel methylene-bridged aryl semicarbazones as potential anticonvulsant agents

A series of aryl semicarbazones containing a methylene bridge in their skeleton were synthesized as anticonvulsant agents. The strategy of introducing a methylene bridge was to increase the flexibility of the structures because of sp3 hybridization. Pharmacological evaluations of the compounds were performed by determination of their effects on pentylenetetrazole-induced seizure parameters and neurotoxicity in mice. The statistical analysis indicated that most of the synthesized compounds showed significant anticonvulsant activity in comparison with the control group. No remarkable neurotoxicity was observed in rotorod test. A QSAR study was performed using multiple linear regressions. The results of the QSAR study confirmed that the compounds with Br at para position of these new derivatives are more potent than para-ethoxy series. Springer Science+Business Media, LLC 2011.