23711-41-3

Basic information

• Product Name: (4E)-4-{[(4-hydroxyphenyl)amino]methylidene}-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
• CAS NO: 23711-41-3
• Molecular Formula: C₁₇H₁₅N₃O₂
• Molecular Weight: 293.3199
• Mol File: 23711-41-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 449.2°C at 760 mmHg
• Flash Point: 225.5°C
• Density: 1.25g/cm³
• Vapor Pressure: 1.1E-08mmHg at 25°C
• Refractive Index: 1.642
• CAS DataBase Reference: (4E)-4-{[(4-hydroxyphenyl)amino]methylidene}-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4E)-4-{[(4-hydroxyphenyl)amino]methylidene}-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(23711-41-3)
• EPA Substance Registry System: (4E)-4-{[(4-hydroxyphenyl)amino]methylidene}-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one(23711-41-3)

Safety Data

• Hazardous Substances Data: 23711-41-3(Hazardous Substances Data)

Usage

General Description

The chemical compound "(4E)-4-{[(4-hydroxyphenyl)amino]methylidene}-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one" is a complex organic molecule with an extended structure. It contains a pyrazolone ring with a methyl and phenyl substituent, as well as an amino group and a hydroxyphenyl group. The compound also features a methylene group connected to the amino and hydroxyphenyl substituents. Its chemical name indicates a potential biological activity, possibly as an inhibitor or modulator of enzymes or receptors, due to the presence of the phenyl and hydroxyphenyl groups that are known to interact with biomolecules. However, further research is needed to fully understand the potential uses and effects of this compound.

Upstream product

• 89-25-8 edaravone 
• 100-63-0 phenylhydrazine 
• 17364-41-9 4-formyl-3-methyl-1-phenylpyrazol-5-one 
• 123-30-8 4-amino-phenol 

Relevant articles and documents

Synthesis, antitumor activity and QSAR studies of some 4-aminomethylidene derivatives of edaravone

A series of aminomethylidene derivatives obtained from 4-formyledaravone were synthesized and characterized by IR, NMR and elemental analysis. All the compounds were screened for their antitumor activity. The compound containing 5-phenylpyrazole moiety (3q) exhibited remarkable antitumor activity in in vitro assays, especially against human breast cancer MDA-MB-361 and MDA-MB-453 cell lines. The most important whole-molecule descriptors for antitumor activity on MDA-MB-453 cells belong to the group of quantum-chemical descriptors.