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2373-79-7 Usage


4-Ethoxycinnamic acid, also known as 4-ethoxy-N-phenylcinnamate, is an organic compound derived from the reaction between the corresponding aryl aldehyde and malonic acid. It is a key intermediate in the synthesis of cholest-5-en-3βyl 3-(4-ethoxyphenyl)-prop-2-enoate, a compound with potential applications in various industries.


Used in Pharmaceutical Industry:
4-Ethoxycinnamic acid is used as an intermediate for the synthesis of cholest-5-en-3βyl 3-(4-ethoxyphenyl)-prop-2-enoate, which may have potential applications in the development of pharmaceuticals targeting specific health conditions. The compound's unique structure allows for further chemical modifications and exploration of its therapeutic properties.
Used in Chemical Synthesis:
In the field of organic chemistry, 4-Ethoxycinnamic acid serves as a valuable building block for the synthesis of various complex organic molecules. Its reactivity and structural features make it a versatile compound for creating novel chemical entities with potential applications in different industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
4-Ethoxycinnamic acid is utilized in research and development for studying its chemical properties, reactivity, and potential applications in various fields. Scientists and researchers can use this compound to explore new reaction pathways, develop innovative synthetic methods, and investigate its biological activities, which may lead to the discovery of new drugs or materials with beneficial properties.

Check Digit Verification of cas no

The CAS Registry Mumber 2373-79-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,7 and 3 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2373-79:
87 % 10 = 7
So 2373-79-7 is a valid CAS Registry Number.

2373-79-7 Well-known Company Product Price

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  • TCI America

  • (E0856)  4-Ethoxycinnamic Acid  >98.0%(GC)(T)

  • 2373-79-7

  • 5g

  • 690.00CNY

  • Detail
  • TCI America

  • (E0856)  4-Ethoxycinnamic Acid  >98.0%(GC)(T)

  • 2373-79-7

  • 25g

  • 2,250.00CNY

  • Detail
  • Alfa Aesar

  • (L06324)  4-Ethoxycinnamic acid, prediminantly trans, 98+%   

  • 2373-79-7

  • 5g

  • 543.0CNY

  • Detail
  • Alfa Aesar

  • (L06324)  4-Ethoxycinnamic acid, prediminantly trans, 98+%   

  • 2373-79-7

  • 25g

  • 2091.0CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017


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More Details:2373-79-7 SDS

2373-79-7Relevant articles and documents

“Effect of the linking unit on the calamitic-shaped liquid crystal: a comparative study of two homologous series of benzoate and cinnamate linked compounds”

Kashyap, Dinesh,Patel, Sunil,Prajapat, Varsha,Sharma, Vinay,Vasava, Dilip

, p. 58 - 70 (2019/08/28)

Two homologous series based on three linking groups have been synthesized and well characterized by elemental analyses and spectroscopic techniques such as Fourier transform infrared [FT-IR] and proton magnetic resonance magnetic resonance [1H NMR] spectroscopy. The mesomorphic properties of these compounds were observed by using optical polarized microscopy (POM) and confirmed by differential scanning calorimetry (DSC) analysis. In this present investigation, we have synthesized two homologous series viz. (E)-4-(3-(4-(tetra decanoyloxy) phenyl) acryloyl) phenyl-4-n-alkoxy benzoate (Series-1) and 4-((E)-3-(4-(((E)-3-(4-n-alkoxy phenyl) acryloyl) oxy) phenyl)-3-oxo prop-1-en-1-yl) phenyl tetradecanoate (Series-2). Both of the series are differing with respect to the first linking group. All the homologous in following series displays LC properties on heating as well as cooling condition except first four homologous (C1 to C4) in series-1 and six homologous (C1 to C6) in series-2. To get more insights, the HOMO, LUMO studies are carried out which supports intramolecular charge transfer interactions in this class of mesogens.

Mesomorphism dependence on molecular rigidity and flexibility

Ranchchh, Avani R.,Bhoya

, p. 43 - 51 (2019/02/24)

A novel homologous series of liquid crystalline properties is synthesized and studied with a view to understand the effect of molecular structure on its thermotropic properties. Novel homologous series consisted of thirteen homologs. All the homologs are enantiotropically smectogenic with absence of nematic property even in the monotropic condition. Textures of the homologs as observed through an optical hot stage polarizing microscopy. The mesophase temperature range vary minimum from 6.0°C to a maximum 37.0°C at the methyloxy and propyloxy derivatives of a series respectively with its thermal stability (Sm–I) 127.0°C. Transition curves of a phase diagram behaved in normal manner. Odd–even effect is observed for Sm–I transition curve.

Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis

Bayer, Theresa,Chakrabarti, Alokta,Lancelot, Julien,Shaik, Tajith B.,Hausmann, Kristin,Melesina, Jelena,Schmidtkunz, Karin,Marek, Martin,Erdmann, Frank,Schmidt, Matthias,Robaa, Dina,Romier, Christophe,Pierce, Raymond J.,Jung, Manfred,Sippl, Wolfgang

, p. 1517 - 1529 (2018/08/01)

Schistosomiasis is a neglected parasitic disease that affects more than 265 million people worldwide and for which the control strategy relies on mass treatment with only one drug: praziquantel. Based on the 3-chlorobenzothiophene-2-hydroxamic acid J1075, a series of hydroxamic acids with different scaffolds were prepared as potential inhibitors of Schistosoma mansoni histone deacetylase 8 (SmHDAC8). The crystal structures of SmHDAC8 with four inhibitors provided insight into the binding mode and orientation of molecules in the binding pocket as well as the orientation of its flexible amino acid residues. The compounds were evaluated in screens for inhibitory activity against schistosome and human HDACs. The most promising compounds were further investigated for their activity toward the major human HDAC isotypes. The most potent inhibitors were additionally screened for lethality against the schistosome larval stage using a fluorescence-based assay. Two of the compounds showed significant, dose-dependent killing of the schistosome larvae and markedly impaired egg laying of adult worm pairs maintained in culture.

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