23730-18-9

Basic information

• Product Name: 4-methyl-N-(tert-butylcarbamoyl)benzenesulfonamide
• Synonyms: 4-methyl-N-(tert-butylcarbamoyl)benzenesulfonamide
• CAS NO: 23730-18-9
• Molecular Weight: 270.353
• Mol File: 23730-18-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-(tert-butylcarbamoyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(tert-butylcarbamoyl)benzenesulfonamide(23730-18-9)
• EPA Substance Registry System: 4-methyl-N-(tert-butylcarbamoyl)benzenesulfonamide(23730-18-9)

Safety Data

• Hazardous Substances Data: 23730-18-9(Hazardous Substances Data)

Upstream product

• 19411-70-2 N-tert-butyl-N'-methylcarbodiimide 
• 4104-47-6 N-sulfinyl-p-toluenesulfonamide 
• 25347-94-8 N-tert-Butyl-N'-methylharnstoff 
• 4083-64-1 Tosyl isocyanate 
• 75-64-9 tert-butylamine 
• 941-55-9 4-toluenesulfonyl azide 
• 201230-82-2 carbon monoxide 
• 98-59-9 p-toluenesulfonyl chloride 
• 1424-52-8 p-tolylsulfonyl isothiocyanate 
• 70-55-3 toluene-4-sulfonamide 
• 1609-86-5 Tert-butyl isocyanate 
• 68899-97-8 N-((tert-butylimino)methylene)-4-methylbenzenesulfonamide 
• 105143-05-3 N-tert-butyl-N'-(toluene-4-sulfonyl)-thiourea 

Relevant articles and documents

Synthesis method of tertiary butyl isocyanate

The invention relates to a synthesis method of tertiary butyl isocyanate. The method comprises the following steps of mixing an inert solvent and para toluene sulfonamide, introducing phosgene at 100DEG C to 120 DEG C, feeding an inert gas for driving gas after reaction, and thus obtaining a first reaction solution; at 0 DEG C to 20 DEG C, dropwise adding tert-butylamine into the first reaction solution, heating and refluxing for 4h or more, and thus obtaining a second reaction solution; separating and purifying the second reaction solution to obtain tertiary butyl isocyanate. According to the synthesis method of tertiary butyl isocyanate, the stability and the yield of the process can be improved, and the purity of the obtained tertiary butyl isocyanate product is higher.

Product-Derived Bimetallic Palladium Complex Catalyzes Direct Carbonylation of Sulfonylazides

A novel product-derived bimetallic palladium complex catalyzes a sulfonylazide-transfer reaction with the σ-donor/π-acceptor ligand CO, and is advantageous given its broad substrate scope, high efficiency, and mild reaction conditions (atmospheric pressure of CO at room temperature). This methodology provides a new approach to sulfonylureas, which are present in both pharmaceuticals and agrochemicals. The synthesis of Glibenclamide on a gram scale further revealed the practical utility of this procedure. Mechanistically, the generation of a bridged bimetallic palladium species derived from the product sulfonylurea is disclosed as the crucial step for this catalytic cycle.