68899-97-8

Upstream product

• 941-55-9 4-toluenesulfonyl azide 
• 119072-55-8 tert-butylisonitrile 
• 98-59-9 p-toluenesulfonyl chloride 
• 21849-40-1 dibromamine-T 
• 66661-88-9 3-tert-Butyl-1,1,2-trimethyl-isothiourea 
• 1424-52-8 p-tolylsulfonyl isothiocyanate 

Downstream Products

• 23730-18-9 4-methyl-N-(tert-butylcarbamoyl)benzenesulfonamide 

Relevant academic research and scientific papers

Cobalt(II)-Catalyzed Isocyanide Insertion Reaction with Sulfonyl Azides in Alcohols: Synthesis of Sulfonyl Isoureas

A Co(II)-catalyzed isocyanide insertion reaction with sulfonyl azides in alcohols to form sulfonyl isoureas via nitrene intermediate has been developed. This protocol provides a new, environmentally friendly, and simple strategy for the synthesis of sulfonyl isourea derivatives by employing a range of substrates under mild conditions.

Atomically defined nanopropeller Fe3Co6Se8(Ph2PNTol)6: Functional model for the electronic metal-support interaction effect and high catalytic activity for carbodiimide formation

Atomically defined interfaces that maximize the density of active sites and harness the electronic metal-support interaction are desirable to facilitate challenging multielectron transformations, but their synthesis remains a considerable challenge. We re

Cobalt(II)-catalyzed bis-isocyanide insertion reactions with sulfonyl azides via nitrene radicals: Chemoselective synthesis of sulfonylamidyl amide and 3-imine indole derivatives

A chemoselective Co(ii)-catalyzed effective synthesis of sulfonylamidyl amide and 3-imine indole derivatives by using isocyanides and sulfonyl azides has been developed. This protocol provides a new, environmentally friendly and simple strategy for the efficient synthesis of the sulfonylamidyl amide and 3-imine indole derivatives with a wide range of substrates in the absence of any oxidants and additives.

A Unified Approach for the Synthesis of Isourea and Isothiourea from Isonitrile and N,N-Dibromoarylsulfonamides

A unified approach has been developed for the synthesis of both isourea and isothiourea in a three-component coupling reaction by treating alcohols or thiols respectively with N,N-dibromoarylsulfonamides and isonitrile and in the presence of K2

Facile, catalyst-free cascade synthesis of sulfonyl guanidines: Via carbodiimide coupling with amines

An expeditious catalyst-free cascade coupling of N,N-dibromoarylsulfonamides with isonitriles and amines via carbodiimide intermediates has been developed. The protocol represents an elegant pathway for sulfonyl guanidines at room temperature within a short time with high yields and wide substrate scope. The carbodiimide intermediate could also be isolated in an appreciable yield.

β-diketiminato nickel imides in catalytic nitrene transfer to isocyanides

The β-diketiminato nickel(I) species [Me3NN]Ni(2-picoline) (1) serves as an efficient catalyst for carbodiimide (RN=C=NR′) formation in the reactions of a range of organoazides N3R with isocyanides R′NC. [Me3NN]Ni(CNR)2 (R = tBu, Ar (Ar = 2,6-Me2C6H3)) species provide carbodiimides RN=C=NAr′ upon reaction with Ar′N3 (Ar′ = 3,5-Me2C6H3). Nitrene transfer takes place via the intermediacy of nickel imides. Reaction of [MexNN]Ni(2-picoline) (x = 2 or 3) with Ar′N3 gives the new dinickel imides {[Me xNN]Ni}2(μ-NAr′) (4 (x = 3) and 5 (x = 2)) as deep purple, diamagnetic substances. The X-ray structure of {[Me 2NN]Ni}2(μ-NAr′) (5) features short Ni-N imide distances of 1.747(2) and 1.755(2) A along with a short Ni-Ni distance of 2.7210(3) A. These dinickel imides 4 and 5 react stoichiometrically with tBuNC to provide the corresponding carbodiimides tBuN=C=NAr′ in good yield. Azide transfer takes place upon reaction of 1 with TMS-N3 to give the square planar nickel(II) azide [Me3NN]Ni(N3)(2-picoline) (7). Stoichiometric reaction of dinickel dicarbonyl {[Me3NN]Ni} 2(μ-CO)2 with organoazides such as Ar′N 3 is sluggish, indicating that 1 is not an efficient catalyst for nitrene transfer from organoazides to CO to form isocyanates RN=C=O.