23730-69-0

Usage

Uses

Used in Pharmaceutical Research:
Aminorex is used as a research chemical for studying the effects of stimulants on the central nervous system. Its ability to increase serotonin and dopamine levels makes it a subject of interest for understanding the mechanisms of action of similar drugs and their potential therapeutic applications.
Used in Controlled Substances Regulation:
Aminorex is used as a reference compound in the development and enforcement of regulations concerning controlled substances. Its classification as a controlled substance helps in monitoring and preventing its illicit use and distribution.

Upstream product

• 2576-47-8 2-bromoethylamine hydrobromide 
• 827-50-9 N-ethyl-N-(2-bromo-ethyl)-aniline 
• 7664-41-7 ammonia 
• 58861-74-8 2-bromoethylamine hydrochloride 
• 103-69-5 N-ethyl-N-phenylamine 
• 92-49-9 N-ethyl-N-(2-chloroethyl)aniline 
• 93111-53-6 N-Ethyl-N-(2-propionamidoethyl)aniline 
• 54939-53-6 N-[2-(N-ethyl-anilino)-ethyl]-phthalimide 
• 16728-93-1 2-[ethyl(phenyl)amino]acetonitrile 

Downstream Products

• 54684-09-2 N-[2-(N-ethyl-anilino)-ethyl]-acetamide 
• 54117-10-1 N-[2-(N-ethyl-anilino)-ethyl]-methanesulfonamide 
• 91637-79-5 N-Aethyl-N-phenyl-N'-(2-hydroxy-aethyl)-aethylendiamin 
• 934962-80-8 N-(butyl)-11-(chloro)-dibenzo[b,f,][1,4]thiazepine-8-carboxamide 
• 934962-79-5 N-(1-phenylethyl)-11-(chloro)-dibenzo[b,f][1,4]thiazepine-8-carboxamide 
• 934962-85-3 N-(2-chlorobenzyl)-11-(chloro)-dibenzo[b,f][1,4]thiazepine-8-carboxamide 
• 934962-93-3 N-(2-bromobenzyl)-11-(chloro)-dibenzo[b,f][1,4]thiazepine-8-carboxamide 
• 934963-01-6 N-(4-fluorobenzyl)-11-(chloro)-dibenzo[b,f][1,4]thiazepine-8-carboxamide 
• 934962-97-7 N-((N-ethyl-N-phenyl)aminoethyl)-11-(chloro)-dibenzo[b,f][1,4]thiazepine-8-carboxamide 
• 23445-62-7 2.2'-Dimethoxy-benzilsaeure-N-<β-(N-ethyl-anilino)-ethyl>-amid 

Relevant academic research and scientific papers

Discovery of small molecule antagonists of TRPV1

Small molecule antagonists of the vanilloid receptor 1 (TRPV1, also known as VR1) are disclosed. Ureas such as 5 (SB-452533) were used to explore the structure activity relationship with several potent analogues identified. Pharmacological studies using electrophysiological and FLIPR Ca2+ based assays showed compound 5 was an antagonist versus capsaicin, noxious heat and acid mediated activation of TRPV1. Study of a quaternary salt of 5 supports a mode of action in which compounds from this series cause inhibition via an extracellularly accessible binding site on the TRPV1 receptor.

Azamacrocycles with N-(Aminoalkyl) Side Chains: Syntheses, Metal Complexes, and Catalysis of Acyl Tranfer Reactions

Azacyclophanes containing ethylene diamine groups and open chain analogues are prepared e. g. by reactions with bromoacetonitrile and subsequent reduction.Metal complexes of the composition L*Cu4Cl8, L*Zn2Cl4, L*Ni6Cl12* 8 H2O, L*Co4(NO3)8* 16 H2O, where

Nucleophilic Ring Opening of 2-Oxazolines with Amines: A Convenient Synthesis for Unsymmetrically Substituted Ethylenediamines

The reaction of 2-alkyl-2-oxazolines with alkyl- and arylamines was investigated.The acid-catalyzed nucleophilic ring opening of the 2-oxazolines yields N-(2-aminoethyl)carboxamides in good to excellent yields with secondary amines and hindered primary amines.The N-(2-aminoethyl)carboxamides were hydrolyzed under acidic or basic conditions to selectively yield unsymmetrically substituted ethylenediamines.