2374-22-3

Usage

Uses

Used in Chemical Synthesis:
1,5-Pentanediol bis(methanesulfonate) is used as a reagent in chemical synthesis for its ability to facilitate the creation of complex molecules. Its high purity and stability contribute to the reliability and efficiency of the reactions it is involved in.
Used in Scientific Research:
In the field of scientific research, 1,5-Pentanediol bis(methanesulfonate) is used as a reagent for its capacity to support precise and controlled chemical reactions, which is essential for the advancement of new discoveries and the development of novel compounds.
Used in Industrial Processes:
1,5-Pentanediol bis(methanesulfonate) is utilized in various industrial processes where its chemical properties are leveraged to produce a range of products, from pharmaceuticals to specialty chemicals, due to its reactivity and stability under diverse conditions.
Used in Safety and Precautionary Measures:
While not a direct application, the need for safety measures and precautions during the handling and storage of 1,5-Pentanediol bis(methanesulfonate) highlights its importance in ensuring the health and safety of workers and the environment in chemical laboratories and industrial settings.

InChI:InChI=1/C7H16O6S2/c1-14(8,9)12-6-4-3-5-7-13-15(2,10)11/h3-7H2,1-2H3

Upstream product

• 111-29-5 1 ,5-pentanediol 
• 124-63-0 methanesulfonyl chloride 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 628-77-3 1,5-diiodopentane 
• 89579-21-5 2,2'-(pentane-1,5-diylbis(oxy))dibenzaldehyde 
• 123-99-9 azelaic acid 
• 103644-25-3 N-(5-{4-[bis-(2-hydroxy-ethyl)-amino]-phenoxy}-pentyl)-phthalimide 
• 103642-07-5 N-{5-[4-(2-methoxy-ethylamino)-phenoxy]-pentyl}-phthalimide 
• 102319-97-1 2-[5-(4-amino-phenoxy)-pentyl]-(3ar,7ac)-hexahydro-isoindole-1,3-dione 
• 103267-35-2 N,N'-bis-[5-(4-nitro-phenoxy)-pentyl]-phthalamide 
• 109037-66-3 (2,4-dichloro-phenoxy)-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102313-88-2 N-[5-(4-nitro-phenoxy)-pentyl]-[1]naphthamide 
• 110047-69-3 4-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102164-88-5 phenoxy-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 110049-64-4 3-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 110047-68-2 2-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102164-74-9 phenyl-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 

Relevant academic research and scientific papers

Process for preparing azelaic acid

A process for preparing azelaic acid is disclosed. In particular, the process for preparing azelaic acid is an ozone free process. The process for preparing azelaic acid comprises a step of decarboxylation of tetra-carboxylic acid in the presence of a organic sulfonic acid.

BIVALENT BROMODOMAIN LIGANDS, AND METHODS OF USING SAME

Described herein are compounds capable of modulating one or more biomolecules substantially simultaneously, e.g., modulating two or more binding domains (e.g., bromodomains) on a protein or on different proteins. For example, in one aspect, a bivalent compound or a pharmaceutically acceptable salt, stereoisomer, metabolite, or hydrate thereof is provided. In another aspect, a method of treating a disease associated with a protein having tandem bromodomains in a patient in need thereof is provided. The method comprises administering to the patient the bivalent compound as described.

Toward analogues of MraY natural inhibitors: Synthesis of 5′-triazole-substituted-aminoribosyl uridines through a Cu-catalyzed azide-alkyne cycloaddition

A straightforward strategy for the synthesis of triazole-containing MraY inhibitors has been developed. It involves the sequential introduction of a terminal alkyne at the 5′ position of an uridine derivative and O-glycosylation with a protected aminoribose leading to an elaborated alkyne scaffold. An efficient Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) allowed the introduction of chemical diversity toward a small library of inhibitors.

Rationally-designed S-chiral bissulfinamides as highly enantioselective organocatalysts for reduction of ketimines

We recently reported the first example of S-chiral organocatalysts, that are highly efficient and enantioselective in substoichometric amounts, and which use a chiral monosulfinamide group as Lewis base to activate trichlorosilane (HSiCl3) to reduce N-arylketimines. Aplausible mechanism involving two molecules of the monosulfinamde catalyst for the activation of HSiCl 3 prompted us to design S-chiral bissulfinamides as new catalysts. We herein describe our findings that an easily prepared S-chiral bissulfinamide bearing a five-methylene linkage not only inherited the excellent substrate generality from the monosulfinamide catalysts, but also exhibited further improved enantioselectivity.

Determination of busulfan in plasma by GC-MS with selected-ion monitoring

A GC-MS technique with selected-ion monitoring is described for the determination of busulfan in plasma. Busulfan is extracted from plasma with methylene chloride and converted to 1,4-diiodobutane. Analysis by GC-MS with selected-ion monitoring (m/z 183) gave a relative standard deviation of ± 4.3% (n = 5) at the 10-ng/ml level.