2374-22-3

Basic information

• Product Name: 1,5-Pentanediol bis(methanesulfonate)
• Synonyms: 1,5-Pentanediol bis(methanesulfonate);1,5-Pentanediol bismethanesulfonate;1,5-Pentanediol di(methanesulfonate);Bis(methanesulfonic acid)pentamethylene ester;Bismethanesulfonic acid 1,5-pentanediyl;1,5-Dimesyloxypentane;5-methylsulfonyloxypentyl methanesulfonate
• CAS NO: 2374-22-3
• Molecular Formula: C₇H₁₆O₆S₂
• Molecular Weight: 260.33
• Mol File: 2374-22-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 35-36 °C(Solv: ethanol (64-17-5))
• Boiling Point: 468.5 ºC at 760 mmHg
• Flash Point: 237.1 ºC
• Appearance: /
• Density: 1.309 g/cm³
• Vapor Pressure: 1.68E-08mmHg at 25°C
• Refractive Index: 1.47
• CAS DataBase Reference: 1,5-Pentanediol bis(methanesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Pentanediol bis(methanesulfonate)(2374-22-3)
• EPA Substance Registry System: 1,5-Pentanediol bis(methanesulfonate)(2374-22-3)

Safety Data

• Hazardous Substances Data: 2374-22-3(Hazardous Substances Data)

Usage

General Description

1,5-Pentanediol bis(methanesulfonate) is a chemical compound often used as a reagent in various chemical reactions. Its chemical formula is C7H16O6S2, reflecting the presence of carbon, hydrogen, oxygen, and sulfur atoms in its structure. Beyond its application in creating other complex molecules, it is known for its high purity and stability, which make it valuable in a variety of scientific and industrial contexts. However, like many chemicals, it must be handled carefully due to the potential for health hazards upon exposure. Therefore, safety measures and precautions are strongly recommended during its application and storage.

InChI:InChI=1/C7H16O6S2/c1-14(8,9)12-6-4-3-5-7-13-15(2,10)11/h3-7H2,1-2H3

Upstream product

• 111-29-5 1 ,5-pentanediol 
• 7143-01-3 Methanesulfonic anhydride 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 123-99-9 azelaic acid 
• 89579-21-5 2,2'-(pentane-1,5-diylbis(oxy))dibenzaldehyde 
• 103644-25-3 N-(5-{4-[bis-(2-hydroxy-ethyl)-amino]-phenoxy}-pentyl)-phthalimide 
• 103642-07-5 N-{5-[4-(2-methoxy-ethylamino)-phenoxy]-pentyl}-phthalimide 
• 102319-97-1 2-[5-(4-amino-phenoxy)-pentyl]-(3ar,7ac)-hexahydro-isoindole-1,3-dione 
• 103267-35-2 N,N'-bis-[5-(4-nitro-phenoxy)-pentyl]-phthalamide 
• 109037-66-3 (2,4-dichloro-phenoxy)-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102313-88-2 N-[5-(4-nitro-phenoxy)-pentyl]-[1]naphthamide 
• 110047-69-3 4-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102164-88-5 phenoxy-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 110049-64-4 3-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 110047-68-2 2-methoxy-benzoic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102164-74-9 phenyl-acetic acid-[5-(4-nitro-phenoxy)-pentylamide] 
• 102008-71-9 phenoxy-acetic acid-[5-(4-amino-phenoxy)-pentylamide] 

Relevant articles and documents

Process for preparing azelaic acid

A process for preparing azelaic acid is disclosed. In particular, the process for preparing azelaic acid is an ozone free process. The process for preparing azelaic acid comprises a step of decarboxylation of tetra-carboxylic acid in the presence of a organic sulfonic acid.

Toward analogues of MraY natural inhibitors: Synthesis of 5′-triazole-substituted-aminoribosyl uridines through a Cu-catalyzed azide-alkyne cycloaddition

A straightforward strategy for the synthesis of triazole-containing MraY inhibitors has been developed. It involves the sequential introduction of a terminal alkyne at the 5′ position of an uridine derivative and O-glycosylation with a protected aminoribose leading to an elaborated alkyne scaffold. An efficient Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) allowed the introduction of chemical diversity toward a small library of inhibitors.

Determination of busulfan in plasma by GC-MS with selected-ion monitoring

A GC-MS technique with selected-ion monitoring is described for the determination of busulfan in plasma. Busulfan is extracted from plasma with methylene chloride and converted to 1,4-diiodobutane. Analysis by GC-MS with selected-ion monitoring (m/z 183) gave a relative standard deviation of ± 4.3% (n = 5) at the 10-ng/ml level.