2374-55-2

Basic information

• Product Name: 2-Propenoic acid, 4-methylphenyl ester
• CAS NO: 2374-55-2
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol File: 2374-55-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 4-methylphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 4-methylphenyl ester(2374-55-2)
• EPA Substance Registry System: 2-Propenoic acid, 4-methylphenyl ester(2374-55-2)

Safety Data

• Hazardous Substances Data: 2374-55-2(Hazardous Substances Data)

Upstream product

• 106-44-5 p-cresol 
• 79-10-7 acrylic acid 
• 814-68-6 acryloyl chloride 
• 86260-02-8 4'-methylphenyl 3-bromopropionate 
• 3840-67-3 sulfuric acid mono-(2-carbamoyl-ethyl) ester 

Downstream Products

• 1620141-67-4 C₁₈H₁₉NO₆S 
• 1586777-28-7 C₂₂H₁₈N₂O₃ 
• 1403986-89-9 4-methylphenyl 2-((2S,3R,4S,5R,6R)-tetrahydro-4-hydroxy-3,5-dimethyl-6-((E)-1-(2-methyloxazol-4-yl)prop-1-en-2-yl)-2H-pyran-2-yl)acetate 
• 1403986-86-6 (2E,4S,5S,6R,7R,8E)-p-tolyl 7-((tert-butyldimethylsilyl)oxy)-5-hydroxy-4,6,8-trimethyl-9-(2-methyloxazol-4-yl)nona-2,8-dienoate 
• 144261-48-3 3-phenyl-3-hydroxy-2-methylene-propanoic acid p-methylphenyl ester 
• 131423-37-5 2-Methylene-pentanedioic acid di-p-tolyl ester 
• 114521-77-6 (1R,2S,4S)-1,4,5,6,7,7-Hexabromo-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid p-tolyl ester 

Relevant articles and documents

Acid- And base-switched palladium-catalyzed γ-C(sp3)-H alkylation and alkenylation of neopentylamine

The functionalization of remote unactivated C(sp3)-H and the reaction selectivity are among the core pursuits for transition-metal catalytic system development. Herein, we report Pd-catalyzed γ-C(sp3)-H-selective alkylation and alkenylation with removable 7-azaindole as a directing group. Acid and base were found to be the decisive regulators for the selective alkylation and alkenylation, respectively, on the same single substrate under otherwise the same reaction conditions. Various acrylates were compatible for the formation of C(sp3)-C(sp3) and C(sp3)-C(sp2) bonds. The alkenylation protocol could be further extended to acrylates with natural product units and α,β-unsaturated ketones. The preliminary synthetic manipulation of the alkylation and alkenylation products demonstrates the potential of this strategy for structurally diverse aliphatic chain extension and functionalization. Mechanistic experimental studies showed that the acidic and basic catalytic transformations shared the same six-membered dimer palladacycle.

Palladium-catalyzed remote C-H functionalization of 2-aminopyrimidines

A straightforward strategy was developed for the arylation and olefination at the C5-position of the N-(alkyl)pyrimidin-2-amine core with readily available aryl halides and alkenes, respectively. This approach was highly regioselective, and the transformation was achieved based on two different (Pd(ii)/Pd(iv)) and (Pd(0)/Pd(ii)) catalytic cycles.

TMSOTf-catalyzed intramolecular seleno-arylation of tethered alkenes: A novel method for the solid-phase synthesis of dihydrocoumarins and coumarins

TMSOTf-catalyzed intramolecular seleno-arylation of tethered alkenes was performed using polystyrene-supported succinimidyl selenide as the selenium source. This catalytic process provides an efficient method for the regioselective synthesis of dihydrocoumarins possessing a seleno-functionality, followed by traceless cleavage of selenium linker to provide dihydrocoumarins and coumarins in good yields and purities.