23746-74-9Relevant academic research and scientific papers
Catalytic Asymmetric Mukaiyama-Mannich Reaction of Cyclic C-Acylimines with Difluoroenoxysilanes: Access to Difluoroalkylated Indolin-3-ones
Li, Jin-Shan,Liu, Yong-Jie,Zhang, Guang-Wu,Ma, Jun-An
, p. 6364 - 6367 (2017)
A catalytic enantioselective Mukaiyama-Mannich reaction of cyclic C-acylimines with difluoroenoxysilanes is reported. (S)-TRIP enables the enantioselective synthesis of a series of novel difluoroalkylated indolin-3-ones bearing a quaternary stereocenter i
Organocatalytic asymmetric synthesis of arylindolyl indolin-3-ones with both axial and central chirality
Fu, Hua,Peng, Fei,Wu, Xudong,Yang, Haijun,Yuan, Xi,Zhu, Changjin
, p. 12648 - 12651 (2020)
An efficient method for chiral phosphoric acid-catalyzed asymmetric synthesis of arylindolyl indolin-3-ones with both axial and central chirality has been developed via the reaction of 3-arylindoles with 2-aryl-3H-indol-3-ones, and the target products were obtained in high yields with excellent enantioselectivity and diastereoselectivity.
Synthesis of N-Fused Seven-Membered Indoline-3-ones via a Palladium-Catalyzed One-Pot Insertion Reaction from 2-Alkynyl Arylazides and Cyclic β-Diketones
Hu, Guiwen,Li, Ping,Sheng, Rong,Zhang, Xiaoxiang,Zhou, Zhiqiang
supporting information, (2020/04/08)
A novel strategy to synthesize N-fused seven-membered multifunctional polycyclic indoline-3-one derivatives via insertion of cyclic C-acylimines into cyclic β-diketones has been described. The reaction proceeded well under mild reaction conditions via a one-pot, three-steps method, which has shown good tolerance of various functional groups.
Chiral phosphoric acid-catalyzed direct asymmetric mannich reaction of cyclic: C -acylimines with simple ketones: Facile access to C2-quaternary indolin-3-ones
Li, Jin-Shan,Liu, Yong-Jie,Li, Shen,Ma, Jun-An
supporting information, p. 9151 - 9154 (2018/08/24)
A chiral Br?nsted acid-catalyzed direct asymmetric Mannich reaction of simple ketones with cyclic C-acylimines has been established for the synthesis of C2-quaternary indolin-3-ones. In the presence of 5-10 mol% chiral phosphoric acid, a series of 2-(2-ox
Multi-site cyclization via initial C-H activation using a rhodium(III) catalyst: Rapid assembly of frameworks containing indoles and indolines
Huang, Ji-Rong,Qin, Liu,Zhu, Yu-Qin,Song, Qiang,Dong, Lin
, p. 2844 - 2847 (2015/03/05)
Tandem multi-site cyclization triggered by Rh(III)-catalyzed C-H activation has been achieved for highly efficient synthesis of spirocycle indolin-3-one (C2-cyclization), benzo[a]carbazole (C3-cyclization) and an unusual indoxyl core (N1-cyclization). In particular, the synthesis of pseudo-indoxyl is typically completed within 10 min, and the reaction tolerates air, water and a range of solvents.
An asymmetric normal-electron-demand aza-Diels-Alder reaction via trienamine catalysis
Liu, Jing-Xin,Zhou, Qing-Qing,Deng, Jin-Gen,Chen, Ying-Chun
, p. 8175 - 8178 (2013/12/04)
An asymmetric normal-electron-demand aza-Diels-Alder cycloaddition of 2-aryl-3H-indol-3-ones and 2,4-dienals was explored via trienamine catalysis of a chiral secondary amine. Multifunctional tricyclic polyhydropyrido[1,2-a] indoles were efficiently constructed in good stereoselectivity (up to 92% ee, >19:1 dr).
Synthesis and Reactions of 2-Phenylindol-3-ones
Hiremath, Shivayogi P.,Biradar, Jaiprakash S.,Mruthyunjayaswamy, B. H. M.
, p. 308 - 310 (2007/10/02)
2-Phenyl-3-aminoindoles (2a-d) have been synthesised and converted into the corresponding 2-phenylindol-3-ones (4a-d), which on reaction with o-phenylenediamine (5a,b) and nitrostyrene give 9-substituted 5H-5a,6-dihydro-5a-phenylindoloquinoxalines
