2377-24-4Relevant academic research and scientific papers
Preparation method of fluoride chalcone
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Paragraph 0019; 0020; 0021; 0022; 0023; 0024; 0025, (2017/07/21)
The invention discloses a preparation method of fluoride chalcone. The preparation method comprises the following steps: firstly, mixing acetonitrile with methanol to obtain a reaction solvent; secondly, adding chalcone and an electrophilic fluorinating a
Fluorination of α,β-unsaturated carbonyl compounds using elemental fluorine
Vints, Inna,Rozen, Shlomo
supporting information, p. 632 - 636 (2016/01/15)
Elemental fluorine was successfully added across the double bond of various α,β-unsaturated carbonyl compounds. A necessary ingredient is a presence of alcohol in the solvent mixture. Unlike all other halogen's addition to olefins, fluorine adds itself in
A new sequential defluorination route to α-fluoro-α,β-unsaturated ketones from trifluoromethyl ketones
Hata, Hiroshi,Kobayashi, Takeshi,Amii, Hideki,Uneyama, Kenji,Welch, John T.
, p. 6099 - 6102 (2007/10/03)
α-Fluoro-α,β-unsaturated ketones were prepared from trifluoromethyl ketones via a sequence involving Mg metal promoted successive double defluorination. Trifluoromethyl ketones were transformed to β,β-difluoroenol silyl ethers which were then coupled with
A general and efficient synthesis of β-ketophosphonates
Coutrot, Philippe,Grison, Claude,Lachgar, Mohamed,Ghribi, Abdelaziz
, p. 925 - 942 (2007/10/02)
The acylation of organocuprates or organolithiated reagents with 2-dialkylphosphonoalkanoyl chlorides or dialkylphosphonofluoroacetyl chlorides represents a general and efficient route to β-ketophosphonates.A Horner reaction between the lithiated anions derived from α-fluoro-β-ketophosphonates and aldehydes leads to 2-fluoro-2-enones whereas the lithiated anions derived from γ-acetylenic-β-ketophosphonates afford enynones. β-ketophosphonate / 2-dialkylphosphonoalkanoyl chloride / dialkylphosphonofluoroacetyl chloride / 2-fluoro-2-enone / enynone
SYNTHESE GENERALE DE β-CETOPHOSPHONATES α-FLUORES PRECURSEURS D'ENONES α-FLUOREES, APPLICATION EN SERIE PYRETHRENIQUE.
Coutrot, Ph.,Grison, C.
, p. 2655 - 2658 (2007/10/02)
Dialkylphosphonoflouracetylchlorides are used to introduce directly the 2-oxophosphonate 1-fluorinated synthons on organometallic reagents.A Horner reaction of the 3 derivated anions with aldehydes gave various 2-fluoro-2-enones.Application to the cis, trans caronaldehyde ethyl ester led to the 2-fluoroethenyl pyrethroid derivatives.
