23772-37-4 Usage
Appearance
Yellow crystalline solid
Usage
Primarily used in organic synthesis and pharmaceutical research
Potential applications
Development of new drugs and compounds for various medical purposes
Category
Indole derivative
Biological activities
Possess a wide range of biological activities, including anti-inflammatory, antimicrobial, and anticancer properties
Structure
Unique structure that makes it a valuable tool for scientists and researchers in the field of medicinal chemistry and drug discovery
Check Digit Verification of cas no
The CAS Registry Mumber 23772-37-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,7 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 23772-37:
(7*2)+(6*3)+(5*7)+(4*7)+(3*2)+(2*3)+(1*7)=114
114 % 10 = 4
So 23772-37-4 is a valid CAS Registry Number.
23772-37-4Relevant academic research and scientific papers
Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity
Chamberlain, Stanley D.,Redman, Aniko M.,Wilson, Joseph W.,Deanda, Felix,Shotwell, J. Brad,Gerding, Roseanne,Lei, Huangshu,Yang, Bin,Stevens, Kirk L.,Hassell, Anne M.,Shewchuk, Lisa M.,Leesnitzer, M. Anthony,Smith, Jeffery L.,Sabbatini, Peter,Atkins, Charity,Groy, Arthur,Rowand, Jason L.,Kumar, Rakesh,Mook Jr., Robert A.,Moorthy, Ganesh,Patnaik, Samarjit
scheme or table, p. 360 - 364 (2011/03/18)
The SAR of C5′ functional groups with terminal basic amines at the C6 aniline of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines is reported. Examples demonstrate potent inhibition of IGF-1R with 1000-fold selectivity over JNK1 and 3 in enzymatic assays.
