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5-Methoxy-6-nitro-2,3-dihydro-1H-indole is a chemical compound derived from the indole family, characterized by the presence of a methoxy group at the 5-position and a nitro group at the 6-position. This yellow crystalline solid, with the molecular formula C9H9NO3, is utilized as a key starting material in the synthesis of a variety of pharmaceuticals and organic compounds. Its potential biological activities have garnered interest, suggesting possible applications in both the medical and chemical fields.

23772-38-5

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23772-38-5 Usage

Uses

Used in Pharmaceutical Synthesis:
5-Methoxy-6-nitro-2,3-dihydro-1H-indole serves as a starting material for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of diverse compounds with potential medicinal properties.
Used in Organic Chemistry:
In the field of organic chemistry, 5-Methoxy-6-nitro-2,3-dihydro-1H-indole is employed as a building block for the synthesis of complex organic molecules. Its reactivity and functional groups enable the formation of a wide range of chemical products, expanding the scope of organic synthesis.
Used in Medicinal Research:
5-Methoxy-6-nitro-2,3-dihydro-1H-indole has been studied for its potential biological activities, which may lead to applications in medicine. Its exploration in research settings aims to uncover its therapeutic potential, possibly contributing to the advancement of treatments for various diseases and conditions.
Used in Chemical Industry:
5-Methoxy-6-nitro-2,3-dihydro-1H-indole's properties make it a valuable component in the chemical industry, where it can be used in the production of dyes, pigments, and other specialty chemicals. Its versatility in chemical reactions allows for its integration into various industrial processes.

Check Digit Verification of cas no

The CAS Registry Mumber 23772-38-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,7 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 23772-38:
(7*2)+(6*3)+(5*7)+(4*7)+(3*2)+(2*3)+(1*8)=115
115 % 10 = 5
So 23772-38-5 is a valid CAS Registry Number.

23772-38-5Relevant academic research and scientific papers

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity

Chamberlain, Stanley D.,Redman, Aniko M.,Wilson, Joseph W.,Deanda, Felix,Shotwell, J. Brad,Gerding, Roseanne,Lei, Huangshu,Yang, Bin,Stevens, Kirk L.,Hassell, Anne M.,Shewchuk, Lisa M.,Leesnitzer, M. Anthony,Smith, Jeffery L.,Sabbatini, Peter,Atkins, Charity,Groy, Arthur,Rowand, Jason L.,Kumar, Rakesh,Mook Jr., Robert A.,Moorthy, Ganesh,Patnaik, Samarjit

scheme or table, p. 360 - 364 (2011/03/18)

The SAR of C5′ functional groups with terminal basic amines at the C6 aniline of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines is reported. Examples demonstrate potent inhibition of IGF-1R with 1000-fold selectivity over JNK1 and 3 in enzymatic assays.

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