23785-52-6

Basic information

• Product Name: 2-amino-3,5-dimethylphenol
• Synonyms: 2-amino-3,5-dimethylphenol;2,4-Dimethyl-6-hydroxyaniline
• CAS NO: 23785-52-6
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.17904
• Mol File: 23785-52-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 158-159 °C(Solv: benzene (71-43-2))
• Boiling Point: 252.7°C at 760 mmHg
• Flash Point: 106.6°C
• Appearance: /
• Density: 1.118g/cm³
• Vapor Pressure: 0.012mmHg at 25°C
• Refractive Index: 1.6
• PKA: 9.98±0.15(Predicted)
• CAS DataBase Reference: 2-amino-3,5-dimethylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-3,5-dimethylphenol(23785-52-6)
• EPA Substance Registry System: 2-amino-3,5-dimethylphenol(23785-52-6)

Safety Data

• Hazardous Substances Data: 23785-52-6(Hazardous Substances Data)

Usage

General Description

2-amino-3,5-dimethylphenol is an organic compound that consists of an amino group (-NH2) and a hydroxyl group (-OH) attached to a phenol ring. It is also known as 3,5-dimethyl-2-aminophenol. This chemical is used in the production of dyes, pigments, and other organic compounds. It has antibacterial and antioxidant properties, and is also used in the formulation of hair dyes and cosmetics. Additionally, 2-amino-3,5-dimethylphenol has been studied for its potential use in medical applications, such as in the development of new drugs and pharmaceutical products.

InChI:InChI=1/C8H11NO/c1-5-3-6(2)8(9)7(10)4-5/h3-4,10H,9H2,1-2H3

Upstream product

• 108-68-9 3,5-Dimethylphenol 
• 5345-09-5 3,5-dimethyl-2-nitrophenol 
• 67-56-1 methanol 

Downstream Products

• 25674-58-2 2-Etiltio-3,5-dimetil-fenolo 
• 25674-57-1 2-methylthio-3,5-dimethylphenol 
• 875852-52-1 benzoic acid-(2-hydroxy-4,6-dimethyl-anilide) 
• 140413-23-6 10-Ethyl-7,9-dimethyl-10H-5-oxa-4,10-diaza-dibenzo[a,d]cyclohepten-11-one 
• 140413-03-2 7,9-Dimethyl-10H-dibenzo[b,f][1,4]oxazepin-11-one 
• 122443-62-3 1-Methoxy-3,5-dimethyl-2-(4-nitro-benzenesulfonyl)-benzene 
• 122443-63-4 3,5-Dimethyl-2-(4-nitro-benzenesulfonyl)-phenol 
• 122443-57-6 4-nitrophenyl 2,4-dimethyl-6-methoxyphenyl sulfide 
• 122443-58-7 4-nitrophenyl 2,4-dimethyl-6-hydroxyphenyl sulfide 
• 25674-51-5 2,4-dimethyl-6-hydroxythiophenol 
• 861795-67-7 2-(2-chloro-acetylamino)-3,5-dimethyl-phenol 
• 861615-81-8 2-amino-4-bromo-3,5-dimethylphenol 

Relevant articles and documents

ONE POT PROCESS FOR THE CONVERSION OF AROYL CHLORIDES TO ACYL THIOUREAS

The present invention disclose an improved one pot process for synthesis of acyl thioureas of formula (I), with yield greater than 80%, from aroyl chlorides of formula (I) wherein, R' is an aryl or a heteroarylene group substituted with one or more groups selected from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino, carboxyl, ester, halogenated hydrocarbon or an aryl or heteroaryl; R" and R"' are selected independently from hydrogen, alkyl, alkylene, alkynyl, alkoxy, alkenyloxy, halo, hydroxyl, nitro, amino or halogenated hydrocarbon.

Quantitative structure-activity relationships in dihydropteroate synthase inhibition by multisubstituted sulfones. Design and synthesis of some new derivatives with improved potency

On the bases of the linear correlation existing for a training set of homomultisubstituted 4-aminodiphenyl sulfones between the computed (INDO) electronic net charges of the SO2 group and the enzymic inhibition data on dihydropteroate synthase from Escherichia coli, seven new heteromultisubstituted derivatives were designed, synthesized, and tested for their inhibition potencies. These compounds were found to be from 5-11 times more effective than 4,4'-diaminodiphenyl sulfone. The implications of the results in the drug design and in the model for the enzyme-inhibitors interaction are discussed.