23837-16-3

Basic information

• Product Name: 1-[bis(phenylsulfanyl)methyl]-4-nitrobenzene
• CAS NO: 23837-16-3
• Molecular Formula: C₁₉H₁₅NO₂S₂
• Molecular Weight: 353.4579
• Mol File: 23837-16-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 520.7°C at 760 mmHg
• Flash Point: 268.7°C
• Density: 1.32g/cm³
• Vapor Pressure: 2.01E-10mmHg at 25°C
• Refractive Index: 1.698
• CAS DataBase Reference: 1-[bis(phenylsulfanyl)methyl]-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[bis(phenylsulfanyl)methyl]-4-nitrobenzene(23837-16-3)
• EPA Substance Registry System: 1-[bis(phenylsulfanyl)methyl]-4-nitrobenzene(23837-16-3)

Safety Data

• Hazardous Substances Data: 23837-16-3(Hazardous Substances Data)

Usage

Appearance

Yellow crystalline solid

Molecular weight

349.45 g/mol

Usage

a. Organic synthesis
b. Reagent in chemical reactions

Potential applications

a. Pharmaceutical industry
b. Agrochemical industry

Structural features

a. Presence of nitro (-NO2) group
b. Presence of sulfanyl (-S) groups

Importance

Building block for the synthesis of various organic compounds

Safety precautions

Handle with caution due to potential risks to health and the environment

Upstream product

• 108-98-5 thiophenol 
• 6425-11-2 4,4'-((4-nitrophenyl)methylene)dimorpholine 
• 4832-52-4 tris(phenylthio)methane 
• 98-95-3 nitrobenzene 
• 1666-13-3 diphenyl diselenide 
• 19479-80-2 (4-nitrophenyl)diazomethane 
• 1747-50-8 4-methyl-N'-[(4-nitrophenyl)methylidene]benzene-1-sulfonohydrazide 
• 882-33-7 diphenyldisulfane 
• 555-16-8 4-nitrobenzaldehdye 
• 619-73-8 4-nitrobenzyl chloride 
• 99-99-0 1-methyl-4-nitrobenzene 
• 367276-81-1 ({[(4S)-1,3-dibenzyl-2-oxo-5-(phenylthio)imidazolidin-4-yl]methyl}thio)acetaldehyde 
• 2403-62-5 p-nitrobenzaldehyde diethyl acetal 
• 2403-53-4 2-(4-nitrophenyl)-1,3-dioxolane 

Downstream Products

• 555-16-8 4-nitrobenzaldehdye 
• 114467-77-5 (difluoro(4-nitrophenyl)methyl)(phenyl)sulfide 

Relevant articles and documents

Dithioacetalization or thioetherification of benzyl alcohols using 9-mesityl-10-methylacridinium perchlorate photocatalyst

We report herein the use of 9-mesityl-10-methylacridinium perchlorate as the visible-light photocatalyst for dithioacetalization or thioetherification of benzyl alcohols in one pot using aerial dioxygen as a terminal oxidant. EPR analysis and Stern-Volmer

Regioselective transition metal- and halogen-free direct dithiolation at C(sp3)-H of nitrotoluenes with diaryl disulfides

Here we describe a potassium tert-butoxide-mediated regioselective direct C-S bond formation at the C(sp3)-H position of nitrotoluenes with disulfides in DMSO at room temperature. The developed reaction generated, in good yields, various dithioacetals having OMe, halogen, and NH2 functionalities at various positions of the arene rings of the disulfides. Interestingly, in the absence of nitrotoluene, diaryl disulfides and diselenides underwent one-carbon homologation to form dithioacetals and diselenoacetals. Synthesized dithioacetals were transformed into 4-nitrobenzaldehyde and 7-(bis(phenylthio)methyl)-1H-indole.

Thioacetalization of aldehydes and ketones in SDS micelles

Aromatic aldehydes have been successfully converted into their corresponding dithioacetal, dithiolane and dithiane derivatives in excellent yields with thiol (benzyl thiol and thiophenol), 1,2-ethanedithiol and 1,3-propanedithiol using trichloroacetic acid in sodium dodecyl sulfate micelles. The same procedure is applicable to ketones, but they need more time to be converted into their thioacetals. Image Presented.