23839-47-6

Usage

Uses

Ignosterol is used in sterol inhibitory studies of novel antifungal compounds.

InChI:InChI=1/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h12,18-22,24,29H,7-11,13-17H2,1-6H3/t19-,20+,21-,22-,24+,27-,28+/m0/s1

Upstream product

• 93-59-4 Perbenzoic acid 
• 632-32-6 (3β,5α)-ergost-8(14)-en-3-ol 
• 632-31-5 5α-ergost-14-en-3β-ol 
• 4042-95-9 3β-acetoxy-5α-ergost-8(14)-ene 
• 5234-54-8 5α-ergosten-(8)-yl-(3β)-acetate 
• 2465-11-4 (22E)-ergosta-7,22-dien-3β-ol 
• 55866-27-8 3β-acetoxy-5α-ergosta-8,14-diene 
• 67-66-3 chloroform 
• 7726-95-6 bromine 
• 7446-08-4 selenium(IV) oxide 
• 64-17-5 ethanol 

Downstream Products

• 632-32-6 (3β,5α)-ergost-8(14)-en-3-ol 

Relevant academic research and scientific papers

Accumulation of ergosta 8,14 dien 3β ol by Saccharomyces cerevisiae cultured with an azasterol antimycotic agent

15-Aza-24-methylene-D-homocholesta-8,14-dien-3β-ol, an antimycotic agent, at a concentration of 75 ng/ml inhibited ergosterol biosynthesis in S. cerevisiae strain 3701B resulting in the accumulation of an unusual sterol. Experimental data presented indicate that this sterol is ergosta-8,14-dien-3β-ol. The accumulation of the compound is supportive of current models of biosynthetic pathways for sterols in yeast and is consistent with inhibition by the azasterol of the Δ14 sterol reductase.