23899-73-2

Basic information

• Product Name: 2(1H)-Pyrimidinone, 4,5-diamino- (6CI,8CI,9CI)
• Synonyms: 2(1H)-Pyrimidinone, 4,5-diamino- (6CI,8CI,9CI);4,5-Diamino-1,2-Dihydropyrimidin-2-One
• CAS NO: 23899-73-2
• Molecular Formula: C₄H₆N₄O
• Molecular Weight: 126.11664
• Product Categories: PYRIMIDINE
• Mol File: 23899-73-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2(1H)-Pyrimidinone, 4,5-diamino- (6CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyrimidinone, 4,5-diamino- (6CI,8CI,9CI)(23899-73-2)
• EPA Substance Registry System: 2(1H)-Pyrimidinone, 4,5-diamino- (6CI,8CI,9CI)(23899-73-2)

Safety Data

• Hazardous Substances Data: 23899-73-2(Hazardous Substances Data)

Usage

Structure

Heterocyclic compound with a pyrimidine ring structure and two amino groups at positions 4 and 5

Applications

Potential use in the pharmaceutical industry for the development of antiviral and anticancer drugs, can also be used as a building block for the synthesis of other organic compounds

Biological activities

Has been studied for its potential therapeutic uses and biological activities

Upstream product

• 2308-57-8 1,3-dihydro-2H-purin-2-one 
• 7664-93-9 sulfuric acid 
• 7732-18-5 water 
• 69099-99-6 4-amino-5-nitropyrimidin-2(1H)-one 

Downstream Products

• 100516-90-3 5,8-dihydro-1H-pteridine-2,6,7-trione 
• 65882-62-4 1H,8H-pteridine-2,7-dione 
• 89324-38-9 1,5-dihydro-pteridine-2,6-dione 
• 2432-24-8 2-Hydroxy-pteridin 
• 89977-50-4 6,7-Dimethyl-2-oxo-1,2-dihydro-pteridin 
• 106823-74-9 N-(4-amino-1,2-dihydro-2-oxopyrimidin-5-yl)benzamide 
• 2308-57-8 1,3-dihydro-2H-purin-2-one 
• 20636-41-3 5-hydroxyuracil 
• 932-52-5 5-Aminouracil 
• 5807-13-6 1,3,6,8-tetrahydro-2,4,5,7-pyrimido<5,4-g>pteridinetetrone 
• 116055-86-8 1,6-dihydropyrimido[4,5-g]pteridine-2,4,7,9(3H,8H)-tetraone 

Relevant articles and documents

Phenyl-imidazolo-cytidine analogues: Structure-photophysical activity relationship and ability to detect single dna mismatch

To expand the arsenal of fluorescent cytidine analogues for the detection of genetic material, we synthesized para-substituted phenyl-imidazolo-cytidine (PhImC) analogues 5a-g and established a relationship between their structure and fluoresce

3-deoxyglucosone and skin

The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.

Amino-substituted pyrimidines, derivatives and methods of use therefor

The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation end products of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.