239074-65-8 Usage
Uses
Used in Pharmaceutical Industry:
3,3-DICHLORO-1,1,1-TRIFLUORO-2-PHENYLPROPAN-2-OL is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique molecular structure allows for the development of new drugs with specific therapeutic properties, contributing to advancements in medicine.
Used in Agrochemical Industry:
In the agrochemical sector, 3,3-DICHLORO-1,1,1-TRIFLUORO-2-PHENYLPROPAN-2-OL is employed as a precursor in the production of agrochemicals. Its role in creating effective pesticides and other agricultural chemicals aids in enhancing crop protection and yield.
Used as a Solvent in Chemical Synthesis:
3,3-DICHLORO-1,1,1-TRIFLUORO-2-PHENYLPROPAN-2-OL is used as a solvent in the synthesis of other chemicals. Its properties make it suitable for facilitating chemical reactions, which is essential in the production of a wide range of compounds.
Used in the Production of Fluorinated Compounds:
As an intermediate, 3,3-DICHLORO-1,1,1-TRIFLUORO-2-PHENYLPROPAN-2-OL is crucial in the manufacture of fluorinated compounds. These compounds have diverse applications across various industries, including in the development of high-performance materials and specialized chemical products.
Safety Considerations:
Given the potential hazards associated with 3,3-DICHLORO-1,1,1-TRIFLUORO-2-PHENYLPROPAN-2-OL, it is imperative to handle this chemical with care. It can be harmful if ingested, inhaled, or comes into contact with the skin. Strict safety protocols and the use of appropriate protective equipment are essential when working with this substance to ensure the safety of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 239074-65-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,9,0,7 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 239074-65:
(8*2)+(7*3)+(6*9)+(5*0)+(4*7)+(3*4)+(2*6)+(1*5)=148
148 % 10 = 8
So 239074-65-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H7Cl2F3O/c10-7(11)8(15,9(12,13)14)6-4-2-1-3-5-6/h1-5,7,15H
239074-65-8Relevant academic research and scientific papers
A facile stereocontrolled approach to CF3-substituted triarylethenes: Synthesis of panomifene
Liu, Xinyu,Shimizu, Masaki,Hiyama, Tamejiro
, p. 879 - 882 (2007/10/03)
The stereoselective preparation and Pd-catalyzed cross-coupling reaction of boronates 2 provides a new general and convenient route to CF 3-substituted triaryl ethenes 3, in which the CF3 and Ar3 groups are cis to each other. The synthetic potential was demonstrated by the total synthesis of panomifene (Ar1 = Ar 3 = Ph, Ar2 = 4-(OHCH2CH2NHCH 2CH2O)-C6H4). Bpin = (pinacolato)boryl.
Stereoselective generation of cis-2-lithio-3-CF3-oxirane via CF3-substituted β-oxido carbenoids. Highly stereoselective synthesis of CF3-substituted tri- and tetrasubstituted oxiranes and tetrasubstituted alkenes
Shimizu, Masaki,Fujimoto, Takuya,Liu, Xinyu,Minezaki, Hiroshi,Hata, Takeshi,Hiyama, Tamejiro
, p. 9811 - 9823 (2007/10/03)
Treatment of 2-substituted 3,3-dichloro-1,1,1-trifluoropropan-2-ols with organolithium reagents R2Li in THF at -98°C stereoselectively produces 2,3-disubstituted 2-lithio-3-trifluoromethyloxiranes with Li and CF3 cis. The reagents react with electrophiles El-X or organoboranes R3BR2 to give CF3-containing tri- and tetrasubstituted oxiranes or tetrasubstituted alkenes, respectively, with high diastereoselectivities.
