239137-39-4

Basic information

• Product Name: 3-Amino-4-bromopyridine
• Synonyms: 3-AMINO-4-BROMOPYRIDINE;4-BROMO-3-AMINOPYRIDINE;4-BROMO-PYRIDIN-3-YLAMINE;4-BROMOPYRIDINE-3-AMINE;3-Amino-4-bromopyridine97%;3-AMINO-4-BROMOPYRIDINE 98%;4-bromopyridin-3-amine;4-Bromo- 3-pyridinamine
• CAS NO: 239137-39-4
• Molecular Formula: C₅H₅BrN₂
• Molecular Weight: 173.01
• EINECS: 1312995-182-4
• Product Categories: Heterocyclic Series;Pyridine;Pyridines;Heterocycle-Pyridine series
• Mol File: 239137-39-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 287.6 °C at 760 mmHg
• Flash Point: 127.7 °C
• Appearance: /
• Density: 1.71 g/cm³
• Vapor Pressure: 34.741mmHg at 25°C
• Refractive Index: 1.333
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 3.88±0.10(Predicted)
• CAS DataBase Reference: 3-Amino-4-bromopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-4-bromopyridine(239137-39-4)
• EPA Substance Registry System: 3-Amino-4-bromopyridine(239137-39-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 239137-39-4(Hazardous Substances Data)

Usage

General Description

3-Amino-4-bromopyridine is a chemical compound that consists of a pyridine ring with an amino group at the 3-position and a bromine atom at the 4-position. It is commonly used as a building block in organic synthesis to produce various pharmaceuticals and agrochemicals. 3-Amino-4-bromopyridine has also been studied for its potential use in the treatment of various diseases, including cancer and inflammation. 3-Amino-4-bromopyridine is considered to be a valuable intermediate in the production of other important chemicals and is widely used in the research and development of new drug candidates.

InChI:InChI=1/C3H6F2O/c1-3(4,5)2-6/h6H,2H2,1H3

Upstream product

• 39910-67-3 4-azidopyridine 

Downstream Products

• 239137-45-2 4-Bromo-3-(2-bromoanilino)pyridine 
• 105752-11-2 4-iodopyridin-3-amine 
• 1395412-24-4 N-[4-(2-fluoro-phenyl)-pyridin-3-yl]-N-methyl-3,5-bis-trifluoromethyl-benzamide 
• 1395412-55-1 N-[4-(3,6-dimethoxy-pyridazin-4-yl)-pyridin-3-yl]-N-methyl-3,5-bis-trifluoromethyl-benzamide 
• 1395412-59-5 N-[4-(5-fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-methyl-3,5-bis-trifluoromethyl-benzamide 
• 1395414-17-1 N-[4-(2,4-dimethyl-thiazol-5-yl)-pyridin-3-yl]-N-methyl-3,5-bis-trifluoromethyl-benzamide 
• 1395415-53-8 N-(4-bromo-pyridin-3-yl)-N-methyl-3,5-bis-trifluoromethyl-benzamide 
• 2922-07-8 2-phenyl-1H-pyrrolo[2,3-c]pyridine 
• 54920-82-0 1,7-naphthyridine-2(1H)-one 
• 869640-41-5 7-benzyl-5,6,7,8-tetrahydro-1,7-naphthyridine-2(1H)-one 
• 146140-99-0 3-amino-4-phenyl-pyridine 
• 244-63-3 betacarboline 
• 7266-32-2 9H-pyrrolo[2,3-b:5,4-c']dipyridine 

Relevant articles and documents

PHOTOLYSIS OF PYRIDYL, QUINOLYL, AND ISOQUINOLYL AZIDES IN HYDROHALOGENOIC ACIDS

Photolysis of 4-azido-pyridine and -quinoline in hydrohalogenoic acids gave the 3-amino-4-halogeno compounds (2) via azirine or azacycloheptatetraene intermediates, whereas their N-oxides (4), under similar conditions, gave the 4-amino-3-halogeno compounds (5) presumably via nitrenium ion intermediates.In the 3-azidoquinoline and 4-azidoisoquinoline series, both free bases (6a, 8a) and N-oxides (6b, 8b) gave similar results to 4-azidopyridine and -quinoline N-oxides (4).