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3-chloro-1-(4-phenylpiperazin-1-yl)propan-1-one is a chemical compound with the molecular formula C15H18ClN2O. It is a derivative of propanone, featuring a chloro group at the 3-position and a 4-phenylpiperazine ring attached to the 1-position. 3-chloro-1-(4-phenylpiperazin-1-yl)propan-1-one is known for its potential applications in the pharmaceutical industry, particularly as a building block for the synthesis of various drugs. Its structure provides a unique combination of functional groups that can be further modified to create a range of bioactive molecules. The compound's properties, such as its reactivity and solubility, can be influenced by the presence of the chloro and phenyl groups, making it a versatile intermediate in organic synthesis.

2392-47-4

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2392-47-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2392-47-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,9 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2392-47:
(6*2)+(5*3)+(4*9)+(3*2)+(2*4)+(1*7)=84
84 % 10 = 4
So 2392-47-4 is a valid CAS Registry Number.

2392-47-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-chloro-1-(4-phenylpiperazin-1-yl)propan-1-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

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More Details:2392-47-4 SDS

2392-47-4Relevant academic research and scientific papers

Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety

Buemi, Maria Rosa,De Luca, Laura,Fais, Antonella,Gitto, Rosaria,Mirabile, Salvatore,Pintus, Francesca,Rapisarda, Antonio,Vittorio, Serena,Germanò, Maria Paola

, (2020/04/21)

Tyrosinase (TYR, EC 1.14.18.1) plays a pivotal role in mammalian melanogenesis and enzymatic browning of plant-derived food. Therefore, tyrosinase inhibitors (TYRIs) can be of interest in cosmetics and pharmaceutical industries as depigmentation compounds

Synthesis of 1,6-disubstituted 4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-7- one derivatives and evaluation of their anticancer activity

Devegowda, Vani Nelamane,Seo, Seon Hee,Pae, Ae Nim,Nam, Ghilsoo,Choi, Kyung Il

scheme or table, p. 647 - 650 (2012/05/04)

Promising anticancer compounds of the type 1,6-disubstituted 4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-7-ones were identified. The target compounds were readily synthesized in a large scale via a sequence of reactions starting from the commercially available primary amines. Their in vitro anti-proliferative activity has been evaluated on prostate (DU-145), colon (HT-29 and HCT-116) and melanoma (A375P) human cancer cell lines. The relationships between the structure and the anticancer activity, covering all tested cancer cell lines, revealed that the compound 5c with 2,4-dimethylphenyl substituent at R2 was the most potent with the IC50 values in the range as low as 0.16 to 0.40 μM.

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