2394-68-5 Usage
Uses
Different sources of media describe the Uses of 2394-68-5 differently. You can refer to the following data:
1. An isoprenoid quinone that enhances nonspecific resistance to bacterial infections. It stimulates phagocytosis in macrophages by modulation of the kinetics of the Fc receptor. It serves as an electron carrier from the flavoprotein to the cytochrome complex in reconstituted proteoliposomes where cytochrome O complex function as an efficient ubiquinol-8 oxidase.
2. CoQ8 has been used as a ligand to activate peroxisome proliferator-activated receptor (PPAR).
Definition
ChEBI: A ubiquinone whose structure comprises a 2,3-dimethoxy-5-methylbenzoquinone nucleus (common to all ubiquinones) and a side chain of eight isoprenoid units.
General Description
Coenzyme Q (CoQ) is a natural compound, which is broadly distributed in living organisms. It is a constituent of the electron transfer system. CoQ contains a benzoquinone moiety and an isoprenoid side chain.
Check Digit Verification of cas no
The CAS Registry Mumber 2394-68-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,9 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2394-68:
(6*2)+(5*3)+(4*9)+(3*4)+(2*6)+(1*8)=95
95 % 10 = 5
So 2394-68-5 is a valid CAS Registry Number.
2394-68-5Relevant articles and documents
A convergent approach to coenzyme Q
Lipshutz, Bruce H.,Bulow, Gerd,Fernandez-Lazaro, Fernando,Kim, Sung-Kyu,Lowe, Richard,Mollard, Paul,Stevens, Kirk L.
, p. 11664 - 11673 (2007/10/03)
Syntheses of coenzyme Q3-8 are described, as well as related systems such as plastoquinone-5. Preparation of the higher homologues of the ubiquinones relies on two new conjunctive reagents, or "linchpins", each of which ultimately corresponds to two or three prenyl units. These allow for attachment of a polyprenyl halide at one end, followed by a Ni(0)-catalyzed cross-coupling at the other terminus with a chloromethylated p-quinone.