68690-48-2

Upstream product

• 68690-52-8 9-(R/S)-p-toluenesulfonyl-3,7,11,15,19-pentamethyleicosa-2Z,6Z,10E,14E,18-pentaen-1-ol benzyl ether 
• 86636-49-9 (2Z,6Z)-1-chloro-8-(benzyloxy)-2,6-dimethylocta-2,6-diene 
• 1393475-04-1 C₁₇H₂₃BrO 
• 657-84-1 sodium tosylate 
• 80373-82-6 (2Z,6Z,10E,14E)-1-Bromo-3,7,11,15,19-pentamethyl-icosa-2,6,10,14,18-pentaene 
• 22488-05-7 (2Z,6Z,10E,14E)-3,7,11,15,19-pentamethylicosa-2,6,10,14,18-pentaen-1-ol 
• 86636-47-7 (2Z,6Z)-8-(benzyloxy)-2,6-dimethyl-1-(tetrahydropyran-2-yloxy)-octa-2,6-diene 
• 52188-74-6 (2Z,6Z)-8-(benzyloxy)-2,6-dimethylocta-2,6-dien-1-ol 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 146033-76-3 all-trans-pentaprenyl chloride 
• 39193-80-1 2-((E)-4-Chloro-3-methyl-but-2-enyloxy)-tetrahydro-pyran 
• 68690-47-1 1-methyl-4-{[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]sulfonyl}benzene 
• 257885-59-9 (2E,6E,10E,14E)-3,7,11,15,19-Pentamethyl-5-(toluene-4-sulfonyl)-icosa-2,6,10,14,18-pentaen-1-ol 
• 68799-82-6 1-chloro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraene 

Downstream Products

• 92464-90-9 9-(R/S)-p-toluenesulfonyl-3,7,11,15,19,23,27-heptamethyloctaeicosa-2Z,6Z,10Z,14Z,18E,22E,26-heptaen-1-ol benzyl ether 
• 2394-68-5 ubiquinone 8 
• 257885-60-2 [(5E,9E,13E,17E,21E,25E)-6,10,14,18,22,26,30-Heptamethyl-12-(toluene-4-sulfonyl)-hentriaconta-5,9,13,17,21,25,29-heptaen-1-ynyl]-trimethyl-silane 
• 5905-41-9 (2Z,6Z,10Z,14Z,18E,22E)-3,7,11,15,19,23,27-heptamethyltriaconta-2,6,10,14,18,22,26-heptaen-1-ol 

Relevant academic research and scientific papers

Synthesis and NMR characterization of (Z, Z, Z, Z, E, E,ω)- heptaprenol

We describe a practical, multigram synthesis of (2Z,6Z,10Z,14Z,18E,22E)-3, 7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaen-1-ol [(Z 4,E2,ω)-heptaprenol, 4] using the nerol-derived sulfone 8 as the key intermediate. Su

A convergent approach to coenzyme Q

Syntheses of coenzyme Q3-8 are described, as well as related systems such as plastoquinone-5. Preparation of the higher homologues of the ubiquinones relies on two new conjunctive reagents, or "linchpins", each of which ultimately corresponds to two or three prenyl units. These allow for attachment of a polyprenyl halide at one end, followed by a Ni(0)-catalyzed cross-coupling at the other terminus with a chloromethylated p-quinone.

GENERAL METHOD OF STEREOSPECIFIC SYNTHESIS OF NATURAL POLYPRENOLS. SYNTHESIS OF BETULAPRENOL-6, -7, -8, AND -9

A stereoselective synthesis of (Z,Z,Z)-12-benzyloxy-1-chloro-2,6,10-trimethyldodeca-2,6,10-triene was achieved starting from (Z,Z)-farnesol.All the components of betulaprenols were synthesized using the C15 block 3 and its lower homologue (C10 block) as t