239473-10-0Relevant academic research and scientific papers
Mixed organofluorine-organosilicon chemistry. 10. Allylation and benzylation of difluoroenoxysilanes. Application to the synthesis of gem- difluoroterpene analogues
Lefebvre, Olivier,Brigaud, Thierry,Portella, Charles
, p. 7233 - 7242 (1999)
Acylsilane and trifluoromethyltrimethylsilane gave, under fluoride initiation, a difluoroenoxysilane which is used in situ in a Lewis acid catalyzed coupling with a prenyl ester or a benzylic bromide. The advantage of this one-pot procedure was illustrate
Convergent synthesis of fluoro and gem-difluoro compounds using trifluoromethyltrimethylsilane
Portella, Charles,Brigaud, Thierry,Lefebvre, Olivier,Plantier-Royon, Richard
, p. 193 - 198 (2007/10/03)
Trifluorotrimethylsilane reacts with acylsilanes to give the corresponding difluoroenoxysilanes via the Brook rearrangement of the alcoholate adducts. The difluoroenoxysilane reacts in situ with various types of electrophilic substrates, leading to gem-di
