2396-25-0Relevant academic research and scientific papers
A hexafluoropropylene directly to the aryl borate method of oxidation heptafluoro isopropylation
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Paragraph 0060-0066; 0119; 0120; 0121; 0122, (2016/10/20)
The invention relates to a method for directly oxidizing arylboronic acid into heptafluoroisopropyl by utilizing hexafluoropropylene. The method comprises the following steps that silver fluoride is used as a fluorine source, under the effect of copper salt, the hexafluoropropylene and the arylboronic acid can be converted into a series of compounds containing heptafluoroisopropyl in organic solvents at the room temperature, and the reaction is also applicable to alkenylboronic acids. The method has the advantage that a series of compounds containing the heptafluoroisopropyl are synthesized through one-step reaction at high selectivity.
Direct heptafluoroisopropylation of arylboronic acids via hexafluoropropene (HFP)
Li, Yajun,Wang, Xiaojun,Guo, Yuwei,Zhu, Zhentong,Wu, Yongming,Gong, Yuefa
supporting information, p. 796 - 799 (2016/01/12)
A novel and straightforward strategy for heptafluoroisopropylation of arylboronic acids at room temperature has been developed. This method, directly using commercial available hexafluoropropene (HFP) as the starting material, provides a new way to synthesize a variety of synthetically useful heptafluoroisopropylated arenes.
