23981-26-2

Basic information

• Product Name: 7-METHOXY-1H-QUINOLIN-2-ONE
• Synonyms: 7-METHOXY-1H-QUINOLIN-2-ONE;7-Methoxyquinolin-2(1H)-one
• CAS NO: 23981-26-2
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18396
• Mol File: 23981-26-2.mol

Chemical Properties

• Melting Point: 199 °C
• Boiling Point: 374.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.199±0.06 g/cm3(Predicted)
• PKA: 11.20±0.70(Predicted)
• CAS DataBase Reference: 7-METHOXY-1H-QUINOLIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHOXY-1H-QUINOLIN-2-ONE(23981-26-2)
• EPA Substance Registry System: 7-METHOXY-1H-QUINOLIN-2-ONE(23981-26-2)

Safety Data

• Hazardous Substances Data: 23981-26-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
7-Methoxy-1H-quinolin-2-one is used as a key intermediate in the synthesis of various organic compounds, particularly for drug development. Its unique structure allows it to be a promising candidate for the creation of new pharmaceuticals, potentially targeting a range of therapeutic areas.
Used in Chemical Synthesis:
In the chemical industry, 7-Methoxy-1H-quinolin-2-one is used as a building block for the synthesis of complex organic molecules. Its reactivity and functional group make it suitable for creating a variety of chemical products, contributing to the advancement of chemical research and development.
Used in Industrial Processes:
7-METHOXY-1H-QUINOLIN-2-ONE's properties may also render it useful in various industrial processes, where its unique characteristics can be leveraged to improve existing technologies or develop new ones. This includes applications in material science, where it could be used to enhance the properties of certain materials or in the development of new materials with specific characteristics.
Overall, 7-Methoxy-1H-quinolin-2-one's potential for diverse applications is underscored by its structural and functional attributes, positioning it as a valuable compound in both pharmaceutical and industrial sectors.

Upstream product

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Downstream Products

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Relevant articles and documents

BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

Described herein are compounds represented by formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of preparing and using the same. The variables Ar, X, R1, R3, R 4, Y1, Y2, n and p are as defined herein.

Preparation method and application of substituted quinoline-2(1H)-one compound

The invention belongs to the field of pharmaceutical chemistry and chemical synthesis, and concretely relates to a preparation method of a substituted quinoline-2(1H)-one compound. The invention provides a preparation method of the substituted quinoline-2(1H)-one compound. The preparation method performs an oxidation reaction on a compound represented by a formula I and an oxidant in a solvent toobtain a compound represented by a formula II. The preparation method has the advantages of simple method, high yield and low cost and is suitable for industrial production. The substituted quinoline-2(1H)-one represented by the formula II is an important intermediate of a variety of pharmaceutical active ingredients.

BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR

The present disclosure describes biaryl triazole compounds, as well as their compositions and methods of use. The compounds inhibit the activity of macrophage migration inhibitory factor and are useful for the treatment of diseases, e.g., inflammatory dis

TRIAZOLO-PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.

OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION

This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.

COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS

The present invention relates to compounds that demonstrate antibacterial activity, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans. In particular this invention relates to compounds useful for the treatment of bacterial infections in warm-blooded animals such as humans, more particularly to the use of these compounds in the manufacture of medicaments for use in the treatment of bacterial infections in warm-blooded animals such as humans.

Synthesis of methoxy-2-quinolones via Pummerer-type cyclization of N-aryl-N-methyl-3-(phenylsulfinyl)propionamides

The thionium ions 10 generated by Pummerer reaction of N-aryl-N-methyl-3-(phenylsulfinyl)propionamides 4 caused not only an electrophilic cyclization reaction producing 2-quinolones 8, but also the formation of the vinyl sulfides 5 and 6 in favor of the l