24014-18-4

Basic information

• Product Name: 3-METHYL-1H-PYRROLE-2-CARBALDEHYDE
• Synonyms: 3-METHYL-1H-PYRROLE-2-CARBALDEHYDE
• CAS NO: 24014-18-4
• Molecular Formula: C₆H₇NO
• Molecular Weight: 109.13
• Mol File: 24014-18-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 95 °C
• Boiling Point: 227.4°C at 760 mmHg
• Flash Point: 96.7°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 0.0775mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 15.50±0.50(Predicted)
• CAS DataBase Reference: 3-METHYL-1H-PYRROLE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-1H-PYRROLE-2-CARBALDEHYDE(24014-18-4)
• EPA Substance Registry System: 3-METHYL-1H-PYRROLE-2-CARBALDEHYDE(24014-18-4)

Safety Data

• Hazardous Substances Data: 24014-18-4(Hazardous Substances Data)

Usage

General Description

3-Methyl-1H-pyrrole-2-carbaldehyde is an organic compound with the chemical formula C6H7NO. It is a colorless to pale yellow liquid with a sweet, caramel-like odor. This chemical is used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a flavoring agent in the food and beverage industry. 3-Methyl-1H-pyrrole-2-carbaldehyde is a versatile intermediate with a wide range of applications in various industrial fields. However, it is important to handle this chemical with caution as it may cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C6H7NO/c1-5-2-3-7-6(5)4-8/h2-4,7H,1H3

Upstream product

• 616-43-3 3-methylpyrrole 
• 68-12-2 N,N-dimethyl-formamide 
• 3284-46-6 benzyl-3-methylpyrrole-2-carboxylate 

Downstream Products

• 94781-48-3 4-bromo-3-methylpyrrole-2-carboxaldehyde 
• 1284257-69-7 4-bromo-3-methyl-2-formyl-N-tosylpyrrole 
• 1284257-67-5 6-(4-bromo-3-methyl-N-tosylpyrrol-2-yl)-1,1-dimethoxy-4,4-dimethyl-5-nitrohexan-2-one 
• 1284257-65-3 4-bromo-3-methyl-2-(2-nitroethyl)-N-tosylpyrrole 
• 90935-74-3 5-formyl-4-methyl-1H-pyrrole-2-carbaldehyde 
• 154367-56-3 7-Methylpyrrolizin-3-one 

Relevant articles and documents

PYRROLOTRIAZINONES AND IMIDAZOTRIAZINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS

The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, R6, X1, X2, m, and n are described herein.

Pyrrolotriazine inhibitors of kinases

The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, PDGFR, HER-1, HER-2, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Metabolites of the Marine Sponge Laxosuberites sp.

The marine sponge Laxosuberites sp. contained a mixture of four 5-alkylpyrrole-2-carboxaldehydes 1, (6'Z)-5-(12'-cyano-6'-dodecenyl)pyrrole-2-carboxaldehyde (2), and (6'Z)-5-(23'-cyano-23'-hydroxy-6'-tricosenyl)pyrrole-2-carboxaldehyde (3).The structures of the metabolites were determined by interpretation of spectral data and by chemical degradation.The cyanohydrin 3 is unusually stable to normal isolation and storage procedures.