2402-91-7

Usage

Uses

Used in Pharmaceutical Industry:
2,3,4-Tribromopyridine is used as a chemical intermediate for the synthesis of various pharmaceutical drugs. Its high reactivity allows it to be a key component in the development of new medications.
Used in Agricultural Industry:
In the agricultural sector, 2,3,4-Tribromopyridine is used as a building block in the production of agrochemicals. It contributes to the creation of effective compounds for crop protection and enhancement of agricultural yields.
Used as a Reagent in Chemical Reactions:
Due to its high reactivity, 2,3,4-Tribromopyridine is employed as a reagent in various chemical reactions. It plays a crucial role in facilitating specific transformations and syntheses in organic chemistry.
Safety Precautions:
It is important to handle 2,3,4-Tribromopyridine with care, as it can be harmful if ingested or comes into contact with the skin or eyes. Proper safety measures should be taken to minimize potential risks during its use in laboratories and industrial settings.

Upstream product

• 626-03-9 3-deazauracil 

Downstream Products

• 861023-90-7 2,3-dibromopyridin-4-amine 
• 127321-90-8 3,4-dibromo-[2]pyridylamine 
• 96246-00-3 3-bromo-2,4-dimethoxypyridine 
• 18677-43-5 2,4-dimethoxypyridine 
• 620-08-6 4-methoxypyridine 

Relevant academic research and scientific papers

Convergent stereoselective synthesis of the visual pigment A2E

(Chemical Equation Presented) A stereoselective total synthesis of the visual pigment A2E has been achieved with use of palladium-catalyzed cross-coupling reactions in all key steps: a regioselective Suzuki or Negishi coupling of 2,4-dibromopyridine, a Sonogashira reaction, and a double Stille cross-coupling to complete the bispolyenyl skeleton.

Synthesis of 2,4-dibromopyridine and 4,4'-dibromo-2,2'-bipyridine. Efficient usage in selective bromine-substitution under palladium-catalysis

We report an efficient method for preparing 2,4-dibromopyridine and 4,4'-dibromo-2,2'-bipyridine from the corresponding nitroazine N-oxide in one step via a tandem nucleophilic substitution-N-oxide reduction process. The one step preparation of 4,4'-dihalo-2,2'-bipyridines from dihalopyridines via a Stille reaction is also described. 4,4'-Dibromo-2,2'-bipyridine undergoes selective mono- or disubstitution processes under palladium catalysis. This short synthetic procedure is an efficient and reliable process for preparing conjugated pyridine and 2,2'-bipyridine building blocks for applications in coordination chemistry and materials science.