96246-00-3

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-2,4-dimethoxy-pyridine is utilized as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the formation of complex molecular structures that can exhibit therapeutic effects. Its unique chemical properties allow it to be a key component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Bromo-2,4-dimethoxy-pyridine is employed as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its role in these applications is to provide a stable and reactive platform for the attachment of functional groups that can target and control various pests and weeds.
Used in Organic Chemistry Research:
3-Bromo-2,4-dimethoxy-pyridine is also used as a research compound in organic chemistry. It serves as a model compound for studying reactions involving heterocyclic structures, which can lead to advancements in synthetic methodologies and the discovery of new chemical entities with potential applications in various fields.

Upstream product

• 67-56-1 methanol 
• 96245-98-6 2,3-dibromo-4-methoxypyridine 
• 96245-99-7 3,4-dibromo-2-methoxypyridine 
• 96245-97-5 3-bromo-4-hydroxy-2(1H)-pyridinone 
• 74-88-4 methyl iodide 
• 18677-43-5 2,4-dimethoxypyridine 
• 2402-91-7 2,3,4-tribromopyridine 
• 626-03-9 3-deazauracil 

Downstream Products

• 18677-43-5 2,4-dimethoxypyridine 
• 1094390-39-2 pre-tenellin B 
• 1309925-77-6 pre-bassianin B 
• 816431-89-7 farinosone A 
• 443770-61-4 (2E,4E)-6-(tert-butyldimethylsilanyloxymethyl)-1-[5-(p-benzyloxyphenyl)-2,4-dimethoxypyridine-3-yl]-4-methylocta-2,4-dien-1-one 
• 443770-62-5 (2E,4E)-6-(hydroxymethyl)-1-[5-(p-benzyloxyphenyl)-2,4-dihydroxypyridine-3-yl]-4-methylocta-2,4-dien-1-one 

Relevant academic research and scientific papers

AZACOUMARIN AND AZATHIOCOUMARIN DERIVATIVES FOR USE IN OPTICALLY ACTIVE DEVICES

The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive chromophore, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and ophthalmic devices. The present invention is also directed to a process of changing the optical properties of said ophthalmic device or a precursor article for manufacturing said ophthalmic device.

Collective synthesis of 4-hydroxy-2-pyridone alkaloids and their antiproliferation activities

A collective synthesis of 4-hydroxy-2-pyridone alkaloids - specifically, pretenellin B, prebassianin B, farinosone A, militarione D, pyridovericin, and torrubiellone C - has been achieved. Key steps include using a strategic convergent method to synthesize the densely substituted pyridone key intermediate by Suzuki-Miyaura cross-coupling reaction, a divergent synthesis approach of target molecules by aldol condensation of pyridone intermediate with homologous aldehydes, and an iterative synthesis of homologous aldehydes with all-trans-polyene backbones. Interestingly, among the six tumor cell lines investigated, torrubiellone C was found to induce potent and apoptotic inhibitory activities on Jurkat T cells with IC50 values of 7.05 μM. Hence, this approach could potentially contribute to the synthesis of bioactive small-molecule libraries as well as drug discovery.

Total synthesis of (±)-cordypyridones A and B and related epimers

"Chemical Equation Presented" Efficient racemic synthesis of two antibacterial and antimalarial natural products, cordypyridones A and B, was achieved from inexpensive, commercially available starting materials In an overall yield of 15% (8% and 7%, respe

Rearrangaments of Azabiphenylenes. The Impact of Nitrogen Number and Position

4-Methoxy-1-azabiphenylene and 1-methoxy-2-azabiphenylene have been synthesized from the appropriate precursor diethynylmethoxypyridines via cobalt-catalyzed cooligomerization with bis(trimethylsilyl)acetylene.When 4-methoxy-1,3-diazabiphenylene was transformed into 1,3-dimethoxyisoquinoline in methanolic sodium methoxide at reflux overnight, 1-methoxy-2-azabiphenylene required longer reflux time and 4-methoxy-1-azabiphenylene required forcing conditions for transformations to occur.The transformations product from the latter was shown to be 1,5-dimethoxy-2-benzazocine and that from the former was established by independent synthesis to be 3-methoxy-1-((E)-2-methoxyethenyl)isoquinoline.The impressive disparity in the products obtained from the methoxydiazabiphenylene and the two methoxyazabiphenylenes can be rationalized by consideration of the locus of methanol addition and sequential electrocyclic reactions.