24033-07-6

Upstream product

• 104-94-9 4-methoxy-aniline 
• 121-33-5 vanillin 
• 3391-75-1 2-methoxy-4-((E)-phenylethenyl)phenol 
• 2101-87-3 p-methoxy-phenylazide 

Downstream Products

• 65639-55-6 2-methoxy-4-(7-methoxy-1,1-dioxo-1,2,3,4-tetrahydro-1λ⁶-benzo[1,4]thiazin-3-yl)-phenol 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 501-58-6 bis(4-methoxyphenyl)diazene 
• 1401204-98-5 C₂₂H₂₂N₂O₄ 
• 58285-79-3 2-methoxy-4-(((4-methoxyphenyl)amino)methyl)phenol 
• 1401205-09-1 C₂₂H₂₂N₂O₃S 
• 84359-04-6 C₁₆H₁₅BrN₂O₃ 
• 65729-35-3 2-methoxy-4-[4-(4-methoxy-phenyl)-3-phenyl-4,5-dihydro-[1,2,4]oxadiazol-5-yl]-phenol 
• 65729-41-1 4-[3-(4-chloro-phenyl)-4-(4-methoxy-phenyl)-4,5-dihydro-[1,2,4]oxadiazol-5-yl]-2-methoxy-phenol 

Relevant academic research and scientific papers

Iron-Catalyzed Nitrene Transfer Reaction of 4-Hydroxystilbenes with Aryl Azides: Synthesis of Imines via C=C Bond Cleavage

C=C bond breaking to access the C=N bond remains an underdeveloped area. A new protocol for C=C bond cleavage of alkenes under nonoxidative conditions to produce imines via an iron-catalyzed nitrene transfer reaction of 4-hydroxystilbenes with aryl azides is reported. The success of various sequential one-pot reactions reveals that the good compatibility of this method makes it very attractive for synthetic applications. On the basis of experimental observations, a plausible reaction mechanism is also proposed.

Synthesis, structure-activity relationships and preliminary mechanism study of N-benzylideneaniline derivatives as potential TLR2 inhibitors

Toll-like receptor 2 (TLR2) can recognize pathogen-associated molecular patterns to defense against invading organisms and has been represents an attractive therapeutic target. Until today, none TLR2 small molecule antagonist have been developed in clinic

Synthesis, characterization and antimicrobial evaluation of some schiff bases and their thiazolidinone products

Six isomeric nitro- and methoxy anilines were condensed with vanillin to obtain Schiff's bases. A new series of 2-(4-hydroxy-3-methoxy phenyl)-1-thiazolidinone derivatives were synthesized by the cyclocondensation of Schiff's bases with mercapto acetic ac

Synthesis and biological evaluation of novel N, N′-disubstituted urea and thiourea derivatives as potential anti-melanoma agents

Two series of urea and thiourea derivatives (1a11a, 1b11b) have been synthesized; all the 22 compounds were reported for the first time. Their anti-proliferative activities against the melanoma cell line B16-F10 were evaluated. Among the compounds tested,

GREEN SYNTHESIS OF ARYL ALDIMINES USING ETHYL LACTATE

The present invention relates to a method for preparing aryl aldimines. In particular, the present invention relates to methods of preparing aryl aldimines that uses environmentally friendly solvent systems.

Silica gel supported sodium hydrogen sulfate as an efficient and reusable heterogeneous catalyst for the synthesis of imines in solvent-free conditions under microwave irradiation

This synthesis of imines has been carried out efficiently by the condensation of carbonyl compounds with amines in the presence of silica gel supported sodium hydrogen sulfate (NaHSO4.SiO2) as a heterogeneous catalyst under microwave irradiation in solvent-free conditions. NaHSO4.SiO2 can be recovered and re-used up to ten times by simple washing with diethyl ether after each use and activated in an oven at 120°C for 1 h, thus rendering the process more economical.

Magnesium perchlorate as an efficient catalyst for the synthesis of imines and phenylhydrazones

Magnesium perchlorate has been found to be an efficient catalyst for the synthesis of imines and phenylhydrazones by the reaction of carbonyl compounds with amines and phenylhydrazine in high yields at room temperatures and in short times. The condensation of less electrophilic carbonyl compounds with poorly nucleophilic amines affords the imines in excellent yields.

Quantitative solid-solid synthesis of azomethines

Twenty preparatively useful azomethines have been quantitatively (100% yield at 100% conversion) obtained as hydrates by grinding together solid anilines with solid benzaldehydes without passing through liquid phases. Unlike (acid catalyzed) azomethine syntheses in solution, the solid-solid condensations proceed 'waste-free'. The solid-state mechanisms have been elucidated by atomic force microscopy (AFM) and in part by scanning near-field optical microscopy (SNOM) in three cases. The results indicate long distance migration of the aldehydes into the lattice of the aniline derivatives. Stumpy protrusions are formed at the direct points of contact but also distance sublimation (100 nm range) is succesful in the case of p-chlorobenzaldehyde and p-nitroaniline. Long-range flow of 4-hydroxybenzaldehyde molecules on its (010)-face into contracting crystals of p-toluidine or p-anisidine occurs along two different cleavage planes. Steep hills and valleys are left behind. The molecular migrations through the sites of contact are interpreted in terms of crystals packing. The ease of these solid-solid condensation reactions relies on the crystal packing.

Some New Schiffs Bases Derived from Vanillin as Possible Anticonvulsants

Twenty new anilino- benzylidenes a ten anilino-methyleneoxy>benzylidenes were synthesised.Seven of these compounds when screened for anticonvulsav-activity aga