24033-90-7

Usage

InChI:InChI=1/C14H13NS/c1-2-6-11(7-3-1)13-10-16-14-9-5-4-8-12(14)15-13/h1-9,13,15H,10H2/t13-/m0/s1

Upstream product

• 20940-07-2 3-phenyl-2H-benzo[b][1,4]thiazine 
• 536-74-3 phenylacetylene 
• 882430-05-9 2-(2-bromophenylthio)-1-phenylethanone 
• 6320-02-1 o-bromothiophenol 
• 16717-64-9 1-azidostyrene 
• 100-42-5 styrene 
• 137-07-5 2-amino-benzenethiol 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 935524-42-8 1,1,1,3,3,3-Hexafluoro-2-(3-phenyl-3,4-dihydro-2H-1,4-benzothiazin-7-yl)-propan-2-ol 
• 1429933-88-9 (S)-3-phenyl-3,4-dihydro-2H-benzo[b][1,4]thiazine 
• 141650-39-7 4-(2,2-Diethoxy-ethyl)-3-phenyl-3,4-dihydro-2H-benzo[1,4]thiazine 

Relevant academic research and scientific papers

An aryl thiol-vinyl azide coupling reaction and a thiol-vinyl azide coupling/cyclization cascade: efficient synthesis of β-ketosulfides and arene-fused 5-methylene-2-pyrrolidinone derivatives

The addition reaction of thiol to vinyl azide has been extensively studied. Variously substituted aryl thiols are all viable for this coupling process. The scope of the other partner is successfully expanded from α-aryl vinyl azide to α-alkyl vinyl azide.

Catalytic Regio- and Stereoselective Alkene Sulfenoamination for 1,4-Benzothiazine Synthesis

An alkene sulfenoamination reaction with 2-aminothiophenol is developed using iodide catalysis. This reaction renders access to useful 1,4-benzothiazines with good functional group compatibility including both electron-donating and electron-withdrawing substituents. The reaction is proposed to proceed through an inversion of the polarity of the thiol functionality. Our mechanistic studies reveal that both thiiranium and thiyl radical pathways are plausible and that the disulfide reagent can also function as a viable substrate in this reaction.

Intermolecular sulfenoamination of alkenes with sulfonamides and: N -sulfanylsuccinimides to access β-sulfonylamino sulfides and dihydrobenzothiazines

An acid-catalyzed intermolecular sulfenoamination reaction of alkenes is developed with sulfonamides as the nitrogen source and N-sulfanylsuccinimides as the sulfur source. This methodology provides a straightforward and general way to synthesize various β-sulfonylamino sulfides with high regio- and diastereoselectivity. The developed method was coupled with intramolecular C-N coupling in a one-pot procedure to afford a series of dihydrobenzothiazine derivatives, a kind of important heterocycle used as biologically active compounds in medicinal chemistry.

Organocatalytic Approach for Transfer Hydrogenation of Quinolines, Benzoxazines and Benzothiazines

Abstract: This study reports on the thiourea dioxide catalyzed transfer hydrogenation of diverse C=N–containing heterocyclic compounds with Hantzsch ester as the hydrogen source. With this cost effective and readily available catalyst, a wide range of 2-s

LXR modulators

A compound of formula I wherein A, X, q, R1, R2a, R2b, R2c, R3a, and R3b are defined herein.