24036-49-5

Upstream product

• 14183-51-8 2H-1,4-benzoxazin-3(4H)-thione 
• 24036-50-8 2-chloro-N-(4,5-dibromo-2-methoxy-phenyl)-acetamide 
• 24036-48-4 2-chloro-N-(5-bromo-2-hydroxyphenyl)acetamide 
• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 24036-52-0 6-bromo-3,4-dihydro-2H-1,4-benzoxazin-3-one 

Relevant academic research and scientific papers

The bromination and nitration of some (2H)-1,4-benzoxazin-3(4H)-ones

Bromination of (2H)-1,4-benzoxazin-3-(4H)-one with bromine in glacial acetic acid gave firstly the 6-bromo and then the 6,7-dibromo compound whilst bromine in chloroform gave mainly the 7-bromo derivative. Bromination of the 6-chloro- and 6-methyl-(2H)-1,4-benzoxazin-3(4H)-ones and (2H)=1,4-benzothiazin-3(4H)-one gave the 7-bromo compounds. Nitration of (2H)-1,4-benzoxazin-3(4H)-one with a sulfuric acid : nitric acid mixture gave the 6-nitro and then 6,8-dinitro compound whilst nitrosation: nitration with sodium nitrite : fuming nitric acid gave mainly the 7-nitro compound. 6-Chloro-(2H)-1,4-benzoxazin-3(4H)-one gave 7-nitro compound.