24037-87-4

Basic information

• Product Name: 2-(2-oxocyclohexyl)isoindoline-1,3-dione
• Synonyms: 2-(2-oxocyclohexyl)isoindoline-1,3-dione;2-(2-oxocyclohexyl)-1H-isoindole-1,3(2H)-dione
• CAS NO: 24037-87-4
• Molecular Formula: C₁₄H₁₃NO₃
• Molecular Weight: 243.25792
• Mol File: 24037-87-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 410°C at 760 mmHg
• Flash Point: 191.1°C
• Appearance: /
• Density: 1.357g/cm³
• Vapor Pressure: 6.24E-07mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: 2-(2-oxocyclohexyl)isoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-oxocyclohexyl)isoindoline-1,3-dione(24037-87-4)
• EPA Substance Registry System: 2-(2-oxocyclohexyl)isoindoline-1,3-dione(24037-87-4)

Safety Data

• Hazardous Substances Data: 24037-87-4(Hazardous Substances Data)

Usage

General Description

The chemical 2-(2-oxocyclohexyl)isoindoline-1,3-dione, also known as phthalimide, is a cyclic imide compound with the molecular formula C8H5NO2. It is a white crystalline solid that is commonly used in the synthesis of various organic compounds, including phthalocyanine dyes, pharmaceuticals, and agricultural chemicals. Phthalimide is also used as a precursor for the production of pesticides and fungicides. It is known for its ability to undergo nucleophilic substitution reactions to form various derivatives, making it a versatile building block in organic synthesis. Additionally, phthalimide has been investigated for its potential use as a precursor for the production of biodegradable polymers.

InChI:InChI=1/C14H13NO3/c16-12-8-4-3-7-11(12)15-13(17)9-5-1-2-6-10(9)14(15)18/h1-2,5-6,11H,3-4,7-8H2

Upstream product

• 136918-14-4 phthalimide 
• 822-87-7 2-Chlorocyclohexanone 
• 1074-82-4 potassium phtalimide 
• 1056477-06-5 2-bromocyclohexanone 

Downstream Products

• 92511-46-1 2-aminocyclohexanone hydrobromide 
• 931-16-8 (+/-)-trans-2-aminocyclohexanol 
• 5399-20-2 2-(2-hydroxy-cyclohexyl)-isoindole-1,3-dione 
• 23198-19-8 cis-2-(methylamino)-1-phenylcyclohexanol 
• 13286-66-3 cis-2-amino-1-phenylcyclohexanol hydrochloride 

Relevant articles and documents

Efficient preparation of biologically important 1,2-amino alcohols

An efficient three-step methodology developed for the preparation of 1,2-amino alcohols. In the first step a rapid coupling between bromoketones and potassium phthalimide in ionic liquid produced-phthalimido ketones in quantitative yields, which is followed by a facile reduction using NaCNBH 3 in acetic acid to give corresponding phthalimido alcohols and finally effecting hydrazinolysis in water at 60C to yield biologically important 1,2-amino alcohols.

IMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF

A compound of formula (I) the process of preparing compounds of formula (I), their pharmaceutical compositions, and the method of treating diseases associated with M 3 muscarinic and/or S--HT 4 serotoninergic receptors.

Regioselectivity of the Reaction of 1-Phenyl-7-oxabicycloheptane with Ammonia, and Mono- and Dimethylamine

The regioselectivity of the reaction of 1-phenylcyclohexene oxide with ammonia, and methyl- and dimethyl-amine in several solvents has been investigated.Ring opening always occurs in a trans fashion, to give as the main product that deriving by nucleophil