24037-87-4

Usage

Uses

Used in Pharmaceutical Industry:
Phthalimide is utilized as a crucial intermediate in the synthesis of various pharmaceuticals. Its reactivity and structural properties make it an ideal candidate for the development of new drugs, contributing to advancements in medicinal chemistry.
Used in Dye Industry:
As a precursor for the production of phthalocyanine dyes, phthalimide plays a significant role in the creation of pigments and dyes used in various applications, including printing inks and colorants for plastics.
Used in Agricultural Chemicals:
Phthalimide is employed in the synthesis of pesticides and fungicides, where its chemical properties allow for the development of effective crop protection agents, enhancing agricultural productivity and crop protection.
Used in Polymer Industry:
Phthalimide has been investigated for its potential as a precursor in the production of biodegradable polymers. This application underscores its utility in developing environmentally friendly materials that can reduce plastic pollution and promote sustainability.
Used in Organic Synthesis:
As a versatile building block in organic synthesis, phthalimide is used in the creation of a wide array of organic compounds through its ability to undergo nucleophilic substitution reactions, thereby expanding its applications across various chemical and industrial domains.

InChI:InChI=1/C14H13NO3/c16-12-8-4-3-7-11(12)15-13(17)9-5-1-2-6-10(9)14(15)18/h1-2,5-6,11H,3-4,7-8H2

Upstream product

• 1074-82-4 potassium phtalimide 
• 822-87-7 2-Chlorocyclohexanone 
• 1056477-06-5 2-bromocyclohexanone 
• 136918-14-4 phthalimide 

Downstream Products

• 92511-46-1 2-aminocyclohexanone hydrobromide 
• 13286-66-3 cis-2-amino-1-phenylcyclohexanol hydrochloride 
• 23198-19-8 cis-2-(methylamino)-1-phenylcyclohexanol 
• 5399-20-2 2-(2-hydroxy-cyclohexyl)-isoindole-1,3-dione 
• 931-16-8 (+/-)-trans-2-aminocyclohexanol 

Relevant academic research and scientific papers

Efficient preparation of biologically important 1,2-amino alcohols

An efficient three-step methodology developed for the preparation of 1,2-amino alcohols. In the first step a rapid coupling between bromoketones and potassium phthalimide in ionic liquid produced-phthalimido ketones in quantitative yields, which is followed by a facile reduction using NaCNBH 3 in acetic acid to give corresponding phthalimido alcohols and finally effecting hydrazinolysis in water at 60C to yield biologically important 1,2-amino alcohols.

Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis

Substituted thiophenes, processes for their preparation, their use as medicament or diagnostic agent. The substituted thiophene derivatives have the following backbone structure: Medicaments comprising compounds of this type are of use for preventing or treating various disorders, such as, respiratory disorders and snoring, acute and chronic disorders, disorders induced by ischemic and/or reperfusion events and by proliferative or fibrotic events, disorders of the central nervous system and lipid metabolism, diabetes, blood coagulation and infection by parasites.

IMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF

A compound of formula (I) the process of preparing compounds of formula (I), their pharmaceutical compositions, and the method of treating diseases associated with M 3 muscarinic and/or S--HT 4 serotoninergic receptors.

Synthesis and conformational assignment of cis- and trans-2-amino-1-arylcyclohexanols

The synthesis of cis- and trans-2-amino-1-arylcyclohexanols 1-8, conformationally restricted analogues of the α-adrenergic drugs norephedrine 9, methoxamine 10, and isopropylmethoxamine 11, is described. trans-Aminoalcohols were obtained through reaction

Regioselectivity of the Reaction of 1-Phenyl-7-oxabicycloheptane with Ammonia, and Mono- and Dimethylamine

The regioselectivity of the reaction of 1-phenylcyclohexene oxide with ammonia, and methyl- and dimethyl-amine in several solvents has been investigated.Ring opening always occurs in a trans fashion, to give as the main product that deriving by nucleophil