13286-66-3Relevant academic research and scientific papers
Synthesis and conformational assignment of cis- and trans-2-amino-1-arylcyclohexanols
Delgado, Antonio,Granados, Ricardo,Mauleon, David,Soucheiron, Inmaculada,Feliz, Miguel
, p. 3186 - 3194 (2007/10/02)
The synthesis of cis- and trans-2-amino-1-arylcyclohexanols 1-8, conformationally restricted analogues of the α-adrenergic drugs norephedrine 9, methoxamine 10, and isopropylmethoxamine 11, is described. trans-Aminoalcohols were obtained through reaction
Regioselectivity of the Reaction of 1-Phenyl-7-oxabicycloheptane with Ammonia, and Mono- and Dimethylamine
Anselmi, Cecilia,Catelani, Giorgio,Monti, Luigi
, p. 205 - 210 (2007/10/02)
The regioselectivity of the reaction of 1-phenylcyclohexene oxide with ammonia, and methyl- and dimethyl-amine in several solvents has been investigated.Ring opening always occurs in a trans fashion, to give as the main product that deriving by nucleophil
Synthesis and pharmacological activity of 1-phenyl-2-oxa-5-azabicyclo[4.4.O]decane derivatives
Balsamo,Lapucci,Macchia,et al.
, p. 563 - 566 (2007/10/02)
Some 1-phenyl-2-oxa-5-azabicyclo[4.4.0]decane derivatives have been synthesized and screened for their activity on the Central Nervous System. Generally all compounds showed both CNS exciting and anticonvulsant activity. configurational and conformational
