2406-34-0

Basic information

• Product Name: CYCLOPENTAMETHYLENEDICHLOROSILANE
• Synonyms: 1,1-Dichloro-1-silacyclohexane;1,1-dichloro-silacyclohexan;CYCLOPENTAMETHYLENEDICHLOROSILANE;1,1-dichlorosilacyclohexane;1,1-dichlorosilinane
• CAS NO: 2406-34-0
• Molecular Formula: C₅H₁₀Cl₂Si
• Molecular Weight: 169.12
• EINECS: 219-301-5
• Mol File: 2406-34-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 172.1°Cat760mmHg
• Flash Point: 52.6°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 1.8mmHg at 25°C
• Refractive Index: 1.461
• CAS DataBase Reference: CYCLOPENTAMETHYLENEDICHLOROSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOPENTAMETHYLENEDICHLOROSILANE(2406-34-0)
• EPA Substance Registry System: CYCLOPENTAMETHYLENEDICHLOROSILANE(2406-34-0)

Safety Data

• Hazardous Substances Data: 2406-34-0(Hazardous Substances Data)

Usage

General Description

CYCLOPENTAMETHYLENEDICHLOROSILANE is a chemical compound with the molecular formula C7H14Cl2Si. It is a colorless liquid with a pungent odor, and it is used as a reagent in organic synthesis and in the manufacturing of silicones and other organosilicon compounds. CYCLOPENTAMETHYLENEDICHLOROSILANE is highly reactive and can undergo hydrolysis in the presence of water, forming corrosive and toxic byproducts. It should be handled with care and stored in a cool, dry place away from moisture and incompatible materials. CYCLOPENTAMETHYLENEDICHLOROSILANE is primarily used in industrial and research settings and should only be handled by trained professionals following proper safety protocols.

InChI:InChI=1/C5H10Cl2Si/c6-8(7)4-2-1-3-5-8/h1-5H2

Upstream product

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Downstream Products

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Relevant articles and documents

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3-Silaazetidine: An Unexplored yet Versatile Organosilane Species for Ring Expansion toward Silaazacycles

Small-ring silacycles are important organosilane species in main-group chemistry and have found numerous applications in organic synthesis. 3-Silaazetidine, a unique small silacycle bearing silicon and nitrogen atoms, has not been adequately explored due to the lack of a general synthetic scheme and its sensitivity to air. Here, we describe that 3-silaazetidine can be easily prepared in situ from diverse air-stable precursors (RSO2NHCH2SiR12CH2Cl). 3-Silaazetidine shows excellent functional group tolerance in a palladium-catalyzed ring expansion reaction with terminal alkynes, giving 3-silatetrahydropyridines and diverse silaazacycle derivatives, which are promising ring frameworks for the discovery of Si-containing functional molecules.

Entecavir intermediate and its preparation method

The invention discloses an entecavir intermediate and a preparation method thereof. A provided preparation method for an entecavir intermediate compound 10 comprises the following steps: performing reducing reaction on an ester compound 11 in an organic solvent under the effect of a reducing agent, so as to obtain the compound 10. A provided preparation method for an entecavir intermediate compound 11 comprises the following steps: reacting a compound 12 with a hydroxyl protection reagent in an organic solvent in the presence of an acid to add a hydroxyl protection group, so as to obtain the compound 11. The preparation methods are cheap and easily available in raw materials, mild in reaction conditions, relatively high in product yield, good in atom economy, friendly to environment, and suitable for industrialized production.