24147-49-7 Usage
Description
2-(diphenylamino)thiazol-4(5H)-one, also known as DPAZT, is a chemical compound characterized by a thiazole ring and a diphenylamino group. It is widely recognized for its potential as a building block in the synthesis of biologically active compounds, making it a significant player in the realms of organic synthesis and pharmaceutical research. DPAZT's unique structure and pharmacological properties render it a valuable asset in drug discovery and development, with additional applications as a fluorescent probe for metal ion detection and in the creation of chemical sensors.
Uses
Used in Pharmaceutical Research:
2-(diphenylamino)thiazol-4(5H)-one is used as a building block for the synthesis of various biologically active compounds, contributing to the development of novel drugs. Its potential in anti-cancer properties has been a focal point of study, indicating its utility in the creation of therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(diphenylamino)thiazol-4(5H)-one is employed as a key intermediate, facilitating the construction of complex molecular structures that are vital for the advancement of chemical research and the pharmaceutical industry.
Used in Chemical Sensors:
2-(diphenylamino)thiazol-4(5H)-one is used as a fluorescent probe for the detection of metal ions, making it an essential component in the development of sensitive and selective chemical sensors for environmental and analytical applications.
Used in Drug Discovery:
DPAZT is utilized in drug discovery as a valuable tool, with its unique structure and pharmacological properties aiding in the identification and optimization of potential drug candidates, particularly in the area of anti-cancer therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 24147-49-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,1,4 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 24147-49:
(7*2)+(6*4)+(5*1)+(4*4)+(3*7)+(2*4)+(1*9)=97
97 % 10 = 7
So 24147-49-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H12N2OS/c18-14-11-19-15(16-14)17(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H,11H2
24147-49-7Relevant articles and documents
Fluorescent Styryl Dyes from 4-Chloro-2-(Diphenylamino)-1, 3-Thiazole-5-Carbaldehyde - Synthesis, Optical Properties and TDDFT Computations
Sekar, Nagaiyan,Umape, Prashant G.,Patil, Sharad R.
, p. 1787 - 1800 (2015)
4-Chloro-2-(diphenylamino)-1,3-thiazole-5-carbaldehyde was reacted with an active methylene compounds, cyanomethyl benzimidazole, cyanomethyl benzothiazole, barbituric acid and Meldrum's acid under Knoevenagel conditions to give novel push-pull styryl chromophores 8a-8d. The synthesized styryl chromophores were characterized by FT-IR, Mass and 1H NMR spectral analysis. The photophysical characteristics of these styryl chromophores were evaluated. The effect of solvent polarity and viscosity on the absorption and emission properties of these chromophores was studied. The structural, molecular, electronic and photophysical parameters of the push-pull dyes were studied by using density functional theory (DFT) and time dependent density functional theory (TDDFT) computations. The ratio of the ground to the excited state dipole moment of the synthesized novel styryl dyes were calculated by Bakhshiev and Bilot-Kawski correlations.
