24152-95-2

Basic information

• Product Name: 2-OXO-2-PYRROLIDIN-1-YLETHANAMINE
• Synonyms: (2-oxo-2-pyrrolidin-1-ylethyl)amine(SALTDATA: FREE);(2-oxo-2-pyrrolidin-1-ylethyl)amine;2-amino-1-(pyrrolidin-1-yl)ethanone
• CAS NO: 24152-95-2
• Molecular Formula: C₆H₁₂N₂O
• Molecular Weight: 128.17
• Mol File: 24152-95-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 262.1°C at 760 mmHg
• Flash Point: 112.3°C
• Appearance: /
• Density: 1.117g/cm³
• Vapor Pressure: 0.0111mmHg at 25°C
• Refractive Index: 1.517
• PKA: 8.17±0.29(Predicted)
• CAS DataBase Reference: 2-OXO-2-PYRROLIDIN-1-YLETHANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-OXO-2-PYRROLIDIN-1-YLETHANAMINE(24152-95-2)
• EPA Substance Registry System: 2-OXO-2-PYRROLIDIN-1-YLETHANAMINE(24152-95-2)

Safety Data

• Hazardous Substances Data: 24152-95-2(Hazardous Substances Data)

Usage

General Description

2-OXO-2-PYRROLIDIN-1-YLETHANAMINE, also known as piracetam, is a chemical compound belonging to the class of nootropic drugs. It is a derivative of the neurotransmitter γ-aminobutyric acid (GABA) and is known for its cognitive enhancement properties. Piracetam has been found to improve memory, learning, and cognitive function, and is used in the treatment of cognitive disorders such as dementia and Alzheimer's disease. Additionally, it has been studied for its potential neuroprotective and neurotrophic effects, making it a promising compound for the treatment of neurological conditions. Piracetam is considered safe and well-tolerated, with few reported side effects, and is available as a prescription medication in some countries.

InChI:InChI=1/C6H12N2O/c7-5-6(9)8-3-1-2-4-8/h1-5,7H2

Upstream product

• 883554-96-9 tert-butyl N-(2-oxo-2-pyrrolidin-1-yl-ethyl)carbamate 
• 4426-24-8 tris(tetrahydropyrrole)boron 
• 56-40-6 glycine 
• 20266-00-6 chloroacetic acid pyrrolidide 

Downstream Products

• 113273-60-2 N,N-tetramethylene-2-(benzylideneamino)ethanamide 
• 88197-48-2 (E)-1-{4-[2-oxo-2-(pyrrolidin-1-yl)ethyl]piperazin-1-yl}-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 
• 1621421-68-8 tert-butyl 2-(benzyloxymethyl)-2-(2-oxo-2-(pyrrolidin-1-yl)ethylcarbamoyl)pyrrolidine-1-carboxylate 
• 949680-17-5 (2-hydroxyphenyl)[5-(pyrrolidin-1-ylcarbonyl)-1H-pyrrol-3-yl]methanone 
• 113273-84-0 (2R,3R,5R)-3-Methyl-2-phenyl-5-(pyrrolidine-1-carbonyl)-pyrrolidine-3-carboxylic acid methyl ester 
• 113273-82-8 (2S,3R,5R)-2-Phenyl-5-(pyrrolidine-1-carbonyl)-pyrrolidine-3-carboxylic acid methyl ester 

Relevant articles and documents

PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE

The present invention provides a compound represented by formula [I] shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme. (in formula [I] above, the structure represented by formula [II] below: represents any of the structures represented by formula group [III] below: R1, R2, R3, and R4 independently represent a hydrogen atom, a fluorine atom, methyl, or the like, R5 represents any of the structures represented by formula group [IV]:

AZOLE-SUBSTITUTED PYRIDINE COMPOUND

The present invention provides a compound represented by formula [I'| shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme, wherein the structure represented by formula [III] shown below represents any of the structures represented by formula group [IV] shown below, wherein R1 represents a hydrogen atom, a fluorine atom, methyl, etc.; R2, R3, and R4 each independently represent a hydrogen atom, a fluorine atom, or methyl; W represents a single bond, C1-3alkanediyl, or the formula -O-CH2CH2-; and ring A represents (a) substituted C4-6cycloalkyl, (b) substituted 4- to 6-membered saturated nitrogen-containing heterocyclyl, (c) substituted phenyl, (d) substituted pyridyl, (e) substituted 2,3-dihydrobenzofuran, (f) 4- to 6-membered saturated oxygen-containing heterocyclyl, etc.

Lithium Bromide/Triethylamine Induced Cycloaddition of N-Alkylidene 2-Amino Esters and Amides to Electron-Deficient Olefins with High Regio- and Stereoselectivity

The imines of 2-amino esters and amides derived from glycine, alanine, and valine are deprotonated by the action of a lithium halide and triethylamine (or DBU).The resulting anionic intermediates undergo highly regio- and stereoselective cycloadditions with a variety of olefins activated by carbonyl-type substituents to produce stereochemically defined derivatives of proline esters or amides.The scope and limitations of this novel cycloaddition are discussed.