241818-03-1

Basic information

• Product Name: BENZENEBUTANOL, DELTA-[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-, (DELTAS)-
• Synonyms: BENZENEBUTANOL, DELTA-[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-, (DELTAS)-;4-(tert-butyldimethylsilyloxy)-4-phenylbutan-1-ol;4-((tert-butyldiMethylsilyl)oxy)-4-(2-chlorophenyl)butan-1-ol;(S)-4-((tert-Butyldimethylsilyl)oxy)-4-phenylbutan-1-ol
• CAS NO: 241818-03-1
• Molecular Formula: C₁₆H₂₈O₂Si
• Molecular Weight: 280.481
• Mol File: 241818-03-1.mol

Chemical Properties

• Boiling Point: 346.4±35.0 °C(Predicted)
• Appearance: /
• Density: 0.951±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 15.04±0.10(Predicted)
• CAS DataBase Reference: BENZENEBUTANOL, DELTA-[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-, (DELTAS)-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZENEBUTANOL, DELTA-[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-, (DELTAS)-(241818-03-1)
• EPA Substance Registry System: BENZENEBUTANOL, DELTA-[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-, (DELTAS)-(241818-03-1)

Safety Data

• Hazardous Substances Data: 241818-03-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
BENZENEBUTANOL, DELTA-[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-, (DELTAS)is utilized as a reactant in the synthesis of various other chemicals, contributing to the development of a range of products across different industries.
Used in Solvent Applications:
BENZENEBUTANOL, DELTA-[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-, (DELTAS)also serves as a solvent, which is essential in numerous chemical processes and reactions. Its properties as a solvent can facilitate the dissolution of various substances, making it a valuable component in the production and manufacturing sectors.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BENZENEBUTANOL, DELTA-[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-, (DELTAS)may be employed in the formulation of drugs, where its solvent properties can aid in the creation of effective and stable medicinal compounds.
Used in Research and Development:
Furthermore, this compound can be found in research and development settings, where it may be used to explore new chemical reactions, synthesize novel compounds, or as a part of studies aimed at understanding its properties and potential applications in various fields.

Upstream product

• 241818-02-0 Acetic acid (S)-4-(tert-butyl-dimethyl-silanyloxy)-4-phenyl-butyl ester 
• 139527-16-5 (S)-4-hydroxy-4-phenylbutyl acetate 
• 4850-50-4 (S)-(-)-1-Phenylbutane-1,4-diol 
• 1056016-27-3 C₂₂H₄₂O₂Si₂ 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 241818-04-2 Toluene-4-sulfonic acid (S)-4-(tert-butyl-dimethyl-silanyloxy)-4-phenyl-butyl ester 
• 241818-05-3 tert-Butyl-dimethyl-((S)-1-phenyl-butoxy)-silane 
• 22135-49-5 (S)-1-phenylbutan-1-ol 

Relevant articles and documents

Chemoselective TBS deprotection of primary alcohols by means of pyridinium tribromide (Py·Br3) in MeOH

A catalytic amount of pyridinium tribromide (Py·Br3) in MeOH chemoselectively deprotects primary TBS ethers in the presence of a variety of other protecting and common functional groups in modest to excellent yields when performed at 0 °C.

A New Approach to Remote Asymmetric Induction in the Diastereoselective Reduction of γ-Keto Esters by Use of a Chiral Podand as Chiral Auxiliary

An efficient 1,7-asymmetric induction was achieved with up to 82percent diastereoisomeric excess (d.e.) in the diastereoselective reduction of the γ-keto ester 4 and o-acetylbenzoate 6 using a chiral podand 2 as a chiral auxiliary.