241824-01-1

Basic information

• Product Name: 4-(2-tert-butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-butyric acid bis-(4-fluoro-phenyl)-pentafluorophenyl-methyl ester
• CAS NO: 241824-01-1
• Molecular Weight: 936.921
• Mol File: 241824-01-1.mol

Chemical Properties

• CAS DataBase Reference: 4-(2-tert-butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-butyric acid bis-(4-fluoro-phenyl)-pentafluorophenyl-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-tert-butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-butyric acid bis-(4-fluoro-phenyl)-pentafluorophenyl-methyl ester(241824-01-1)
• EPA Substance Registry System: 4-(2-tert-butoxy-1-tert-butoxycarbonyl-ethylcarbamoyl)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-butyric acid bis-(4-fluoro-phenyl)-pentafluorophenyl-methyl ester(241824-01-1)

Safety Data

• Hazardous Substances Data: 241824-01-1(Hazardous Substances Data)

Upstream product

• 48067-24-9 O-tert-butyl L-serine tert-butyl ester 
• 241823-99-4 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-[bis-(4-fluoro-phenyl)-pentafluorophenyl-methyl] ester 
• 241823-93-8 2,3,4,4',4'',5,6-heptafluoro-triphenylmethanol 
• 241823-94-9 1-[Chloro-bis-(4-fluoro-phenyl)-methyl]-2,3,4,5,6-pentafluoro-benzene 
• 144120-54-7 Nα-(9-fluorenylmethoxycarbonyl)-L-glutamic acid α-allyl ester 
• 345-92-6 4,4'-Difluorobenzophenone 
• 344-04-7 bromopentafluorobenzene 

Relevant articles and documents

Modified Trityl Ester Protecting Groups in Peptide Synthesis

The novel, sterically demanding heptafluorotrityl- and phenylfluorenyl ester protecting groups were developed for the pro tection of the γ-carboxy group of glutamic acid. These trityl-type protecting groups exhibit a markedly increased stability compared to triphenylmethyl esters, and in addition the very mild cleavage conditions make their selective removal in the presence of other acid labile protecting groups such as tBu possible.