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1-(2-nitrophenylcarbonyl)-1,2,3,4-tetrahydroquinoline is a chemical compound belonging to the class of quinoline derivatives. It features a tetrahydroquinoline backbone with a 2-nitrophenylcarbonyl group attached at the 1 position, making it a versatile chemical with potential applications in the pharmaceutical industry and other fields.

24223-25-4

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24223-25-4 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-nitrophenylcarbonyl)-1,2,3,4-tetrahydroquinoline is used as a building block for the synthesis of various biologically active compounds due to the presence of the nitrophenyl group. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Drug Development:
1-(2-nitrophenylcarbonyl)-1,2,3,4-tetrahydroquinoline is used as a precursor in drug development, particularly for creating anti-malarial or anti-microbial agents, thanks to its quinoline backbone, which is known for its bioactivity and potential medicinal properties.

Check Digit Verification of cas no

The CAS Registry Mumber 24223-25-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,2,2 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 24223-25:
(7*2)+(6*4)+(5*2)+(4*2)+(3*3)+(2*2)+(1*5)=74
74 % 10 = 4
So 24223-25-4 is a valid CAS Registry Number.

24223-25-4Relevant academic research and scientific papers

Orally active, nonpeptide vasopressin V2 receptor antagonists: A novel series of 1-[4-(benzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepines and related compounds

Ogawa, Hidenori,Yamashita, Hiroshi,Kondo, Kazumi,Yamamura, Yoshitaka,Miyamoto, Hisashi,Kan, Keizo,Kitano, Kazuyoshi,Tanaka, Michinori,Nakaya, Kenji,Nakamura, Shigeki,Mori, Toyoki,Tominaga, Michiaki,Yabuuchi, Youichi

, p. 3547 - 3555 (2007/10/03)

This paper describes a novel series of nonpeptide vasopressin V2 receptor antagonists. It has been demonstrated that the 1-[4- (benzoylamino)benzoyl]-2,3,4,5-1H-benzazepines and 1-[4- (benzoylamino)benzoyl]-2,3,4,5-1H-1,5-benzodiazepines show a high affinity for V2 (and V(1a)) receptors. Among the 1-[4-(benzoylamino)benzoyl]-2,3,4,5- 1H-benzazepine series, compounds with an alkylamino group on the benzazepine ring have been shown to have oral activity. A lipophilic group at the ortho position on the terminal benzoyl ring is important for both high V2 receptor affinity and oral activity. On the basis of these favorable properties, clinical testing of 31b has begun for use as an oral and iv aquaretic agent.

BENZOHETEROCYCLIC COMPOUNDS

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, (2008/06/13)

Novel benzoheterocyclic compounds of the formula: STR1 wherein R. sup.1 is H, halogen, alkyl, optionally substituted amino, alkoxy; R 2 is H, halogen, alkoxy, phenyialkoxy, OH, alkyl, optionally substituted amino, carbamoyl-alkoxy, optionally substituted

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