24224-99-5 Usage
General Description
Benzenesulfonyl cyanide is a chemical compound with the formula C7H5NO2S. It is a white, crystalline solid that is soluble in polar solvents such as acetone and methanol. Benzenesulfonyl cyanide is used as a reagent in organic synthesis, particularly in the formation of sulfonamides and other functionalized benzenesulfonamide derivatives. It reacts with primary and secondary amines to form sulfonamides, and with Grignard reagents to produce benzenesulfonamides. Additionally, benzenesulfonyl cyanide has been studied as a potential precursor for the formation of various pharmaceuticals and agricultural chemicals. It is important to handle this compound with caution, as it is toxic if ingested or inhaled, and can cause skin and eye irritation upon contact.
Check Digit Verification of cas no
The CAS Registry Mumber 24224-99-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,2,2 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 24224-99:
(7*2)+(6*4)+(5*2)+(4*2)+(3*4)+(2*9)+(1*9)=95
95 % 10 = 5
So 24224-99-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H5NO2S/c8-6-11(9,10)7-4-2-1-3-5-7/h1-5H
24224-99-5Relevant articles and documents
Nickel-Catalyzed Reductive Thiolation of Unactivated Alkyl Bromides and Arenesulfonyl Cyanides
Rao, Weidong,Wang, Fei,Wang, Shun-Yi
, p. 8970 - 8979 (2021/07/19)
The cross-electrophile coupling between unactivated alkyl bromides with arenesulfonyl cyanides catalyzed by Ni(acac)2under reductive conditions to form unsymmetrical sulfides is developed. This approach for sulfide synthesis is practical, relies on available, unfunctionalized materials such as alkyl (pseudo)halides, and is scalable. This catalytic strategy provides a complementary method for the preparation of unsymmetrical alkyl-aryl sulfides under mild conditions with good functional group tolerance.
Process for producing 2-azabicyclo[2.2.1]hept-5-en-3-one
-
, (2008/06/13)
2-Azabicyclo[2.2.1]hept-5-en-3-one is prepared by a process comprising: continuously mixing a substituted sulfonyl cyanide represented by formula (I): R—SO2CN??(I), wherein R represents an alkyl group or a phenyl group or a substituted phenyl group, with cyclopentadiene; and then continuously adding the resultant reaction solution to water or to a mixed solvent comprising water and a hydrocarbon solvent under the condition that the pH of the present reaction mixture ranges from 4 to 7.
