24251-93-2

Upstream product

• 111-83-1 1-bromo-octane 
• 105-53-3 diethyl malonate 
• 1472-85-1 diethyl octylmalonate 
• 629-27-6 1-Iodooctane 

Downstream Products

• 45235-48-1 2-octyl-1-decanol 
• 376395-34-5 diethyl N-benzyl-3,4-(2,2-dioctyl-1,3-propylenedioxy)pyrrole-2,5-dicarboxylate 
• 619-39-6 2-octyldecanoic acid 

Relevant academic research and scientific papers

Immobilization of components in polymer membrane-based calcium-selective bulk optodes

A large variety of optical sensors based on thin plasticized PVC membranes have been realized in the past. The organic membrane (bulk optode) contains the analyte recognition molecule such as a selective neutral ionophore, a H+-selective chromoionophore, and Ilpophllic anionic sites. In order to improve the lifetime of analytically relevant sensing layers, their active components are covaiently immobilized to the polymeric matrix. Different Ca2+-selective bulk optodes with mobile or fixed chromolonophores and anionic sites are characterized and discussed with respect to sensor behavior such as dynamic range, repeatability, response time, selectivity, and lifetime. In general, the response time increases upon immobilization of components owing to limited diffusion within the membrane phase, whereas the lifetime is enhanced drastically by a hindered loss of membrane components into the sample.

Synthesis and Solution Properties of a Double-Tailed Quaternary Ammonium Surfactant with a Protrudent Head Group

Modification of the molecular structure of surfactants is an effective method for exploring their self-assembly. A double-tailed quaternary ammonium surfactant with a protrudent head group, namely 2-octyldecyltrimethylammonium bromide (2-ODTAB) was synthesized, and the solution properties were investigated by surface tension, dynamic light scattering, and cryogenic TEM. A comparative study was also performed on the traditional double-tailed homologue surfactants dioctyldimethylammonium bromide (8-8), didecyldimethylammonium bromide (10-10), and didodecyldimethylammonium bromide (12-12). The results showed that 2-ODTAB was more effective at lowering surface tension and in forming stable vesicles than traditional double-tailed surfactants with similar alkyl chain length. The reason is attributed to the improved structure of 2-ODTAB, in which the two alkyl tails are connected to the ionic head group by one carbon atom. This structure imparts more freedom to the head group and thus favors formation of more stable aggregates at low concentration. In addition, the lower limit of the alkyl chain length of the double-tailed surfactants for forming stable vesicles was illustrated.

Diaryldiazepine Prodrugs for the Treatment of Neurological and Psychological Disorders

The present invention provides prodrug compounds of diaryldiazepine drug compounds.

Synthesis of a tetraamido macrocycle ligand from a novel diamidodiol

A new composition of matter for a diamidodiol and a method for preparing the diamidodiol. The exemplary diamidodiol has the formula C15H30N2O4 and is prepared by reacting a first quantity of 2-amino-2-methyl-1-propanol with a second quantity of a di-substituted malonyl dichloride (i.e., diethylmalonyl dichloride), preferably in ethyl acetate as solvent. A tetraamido macrocycle is prepared from the diamidodiol in two steps by oxidizing the diamidodiol to form a diacid followed by coupling using a known procedure of the diacid with an aryl diamine (e.g., 1,2-diaminobenzene) to yield the tetraamido macrocycle.

3,4-Alkylenedioxypyrroles: Functionalized derivatives as monomers for new electron-rich conducting and electroactive polymers

New functionalized derivatives of 3,4-ethylenedioxypyrrole (EDOP, 5a) and 3,4-(1,3-propylenedioxy) pyrrole (ProDOP, 5b) as especially electron-rich monomers which yield highly electroactive and stable conducting polymers useful for a diverse set of applications have been synthesized. N-Alkylations of ProDOP were carried out to yield a variety of ProDOP derivatives having alkyl, sulfonatoalkoxy, glyme, and glyme alcohol pendant chains. Iodization of EDOP and ProDOP via iodo-decarboxylation afforded iodo-functionalized derivatives useful for subsequent aryl coupling chemistry. N-Protection and formylation of EDOP, followed by Knoevenagel condensation of the resultant 2-formyl-EDOP with aryl acetonitrile derivatives, led to 1-cyano-2-(2-(3,4-ethylenedioxypyrryl))-1-(2-thienyl)vinylene (23) (Th-CNV-EDOP) and 1-cyano-2-(2-(3,4-ethylenedioxypyrryl))-1-(2-(3,4-ethylenedioxythienyl) vinylene (26) (EDOT-CNV-EDOP). A 14-crown-4-ether 34 based dioxypyrrole was synthesized with a cavity potentially useful for lithium ion coordination and sensing in the resultant electroactive polymer. C-Alkylated ProDOPs (43a, 43b, and 43c) containing octyl, ethylhexyl, and dioctyl substituents appended to the central methylene of the propylene bridge, were prepared as monomers for potentially soluble π-conjugated polymers.

FACTORS GOVERNING PRODUCT DISTRIBUTION IN THE OXIDATION OF ALKENES BY MANGANESE(III) ACETATE IN ACETIC ACID AND ACETIC ANHYDRIDE

A systematic investigation has been carried out into the effect of different reaction parameters on the oxidation of oct-1-ene by manganese(III) acetate in acetic acid and acetic anhydride.The most important factor in dictating the ratio of products is the composition of the solvent.In the absence of anhydride γ-decanolactone is virtually the sole product.Even small quantitites of anhydride lead to the lactone being replaced by other products derived from cationic intermediates C6H13CH(1+)CH2COX (X = OH or OAc).Further increases in the amount of anhydride encourage the formation of decanoic acid until, in 90percent anhydride, this becomes the predominant product.The results cannot be interpreted simply in terms of competition for the alkene by the radicals (.)CH2CO2H and (.)CH2COOCOCH3.Decanoic acid formation is also favoured by low temperatures, low concentration of oxidants, and by the addition of acetate ions.A comparision is made of the efficiency of addition when the initiating species is manganese(III) or a peroxide.