242815-91-4

Basic information

• Product Name: 7-CHLORO-TETRAZOLO[1,5-A]PYRIDINE
• Synonyms: 7-CHLORO-TETRAZOLO[1,5-A]PYRIDINE;6-Chloro-tetrazolo[1,5-a]pyridine
• CAS NO: 242815-91-4
• Molecular Formula: C5H3ClN4
• Molecular Weight: 154.56
• Mol File: 242815-91-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 7-CHLORO-TETRAZOLO[1,5-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLORO-TETRAZOLO[1,5-A]PYRIDINE(242815-91-4)
• EPA Substance Registry System: 7-CHLORO-TETRAZOLO[1,5-A]PYRIDINE(242815-91-4)

Safety Data

• Hazardous Substances Data: 242815-91-4(Hazardous Substances Data)

Usage

General Description

7-Chloro-tetrazolo[1,5-a]pyridine is a chemical compound that is often used in various areas of scientific study, primarily in organic and medicinal chemistry. Its molecular formula is C5H3ClN4, indicating that it consists of carbon, hydrogen, chlorine, and nitrogen atoms. The chemical falls under the tetrazolo[1,5-a]pyridine family of compounds, which are known for their potential biological activity and are often used as building blocks in designing drugs. Overall, 7-Chloro-tetrazolo[1,5-a]pyridine is a valuable compound in research for its synthetic versatility and potential medicinal applications.

Upstream product

• 16110-09-1 2,5 dichloropyridine 
• 1851-22-5 3-chloropyridine-N-oxide 
• 4214-79-3 5-chloro-2-pyridinol 

Downstream Products

• 1606181-83-2 6-chloro-2-phenyl-[1,2,4]triazolo[1,5-a]pyridine 

Relevant articles and documents

One-step conversion of pyridine N-oxides to tetrazolo[1,5-a]pyridines

(Chemical Equation Presented) Pyridine N-oxides were converted to tetrazolo[1,5-a]pyridines in good to excellent yield by heating in the presence sulfonyl or phosphoryl azides and pyridine in the absence of solvent. Various sulfonyl and phosphoryl azides were screened for reactivity under a standard set of conditions. Diphenyl phosphorazidate was the most convenient reagent and gave high yields. Reaction optimization, scope, and scalability are discussed.

SNAr azidation of phenolic functions utilizing diphenyl phosphorazidate

A useful method for the synthesis of aryl azides via SNAr reaction of phenol derivatives using diphenyl phosphorazidate (DPPA) as an azidation reagent was developed. Various phenol derivatives bearing electron-withdrawing groups were converted into the corresponding aryl azides in a single step. This method is easy to perform and enables the preparation of aryl azides without the use of explosive azide sources.