24293-67-2

Upstream product

• 90-02-8 salicylaldehyde 
• 84-11-7 9,10-phenanthrenequinone 
• 27318-90-7 1,10-phenanthroline-5,6-dione 
• 60633-78-5 2-(2-bromoethoxy)benzaldehyde 
• 85-01-8 phenanthrene 

Downstream Products

• 69-72-7 salicylic acid 
• 58484-85-8 2-(2-methoxyphenyl)-1H-phenanthro[9,10-d]-imidazole 
• 1346755-05-2 6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene)cyclohexa-2,4-dien-1-one 

Relevant academic research and scientific papers

Fluorescence resonance energy transfer from a bio-active imidazole derivative 2-(1-phenyl-1H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenol to a bioactive indoloquinolizine system

Novel donor imidazole derivative, 2-(1-phenyl-1H-imidazo [4,5-f][1,10]phenanthrolin-2-yl)-phenol (PIPP) was screened as highly sensitive chemisensor for transition metal ions and it can be used as a "multi-way" optically switchable material. Solvatochromi

A selective and sensitive phenanthroimidazole-based "reactive" ratiometric sensor for recognition of Hg2+ ions in aqueous solution

Based on specific reactivity of the vinyloxy group to Hg2+ ions, a new ratiometric phenanthroimidazole-based fluorescent sensor, 2-(2-(vinyloxy)phenyl)-1H-phenanthro[9,10-d]imidazole, is prepared. The selectivity of the probe toward Hg2+/

Two phenanthroimidazole turn-on probes for the rapid detection of selenocysteine and its application in living cells imaging

Detection of selenocysteine (Sec) content in cells by fluorescence probe is of great significance for the identification of human related diseases. To achieve fast and sensitive detection of Sec, two isomers A4 and B4 as turn-on fluorescent probes to detect Sec were designed and synthesized. Both A4 and B4 display fast turn-on response, high selectivity and sensitivity toward Sec, which can be applied for fluorescence imaging of Sec in living cells. Compared with B4, A4 has a larger Stokes shift (125 nm), wider pH range (5–10) and lower detection limit (65.4 nM) due to its ESIPT (excited state intramolecular proton transfer) effect. In view of the detection performance of these two probes, they can be used as effective tools for detecting Sec in biological systems.

Synthesis of 5-(4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzylidene)thiazolidine-2,4-dione as promising DNA and serum albumin-binding agents and evaluation of antitumor activity

A series of phenanthro[9,10-d]imidazole/oxazole and acenaphtho[1,2-d]imidazole with different aryl groups at C2-position has been synthesized. These compounds were in vitro evaluated for antitumor activity against a panel of 60 human cancer cell lines. Co

Photoenolization via excited state proton transfer and ion sensing studies of hydroxy imidazole derivatives

A light stimulated photo-enolization in hydroxy imidazole systems (o-hydroxynaphthyl phenanthroimidazole, 3 and o-hydroxyphenyl phenanthroimidazole, 4) by excited state proton transfer induces “turn Off” fluorescence and ratiometric changes in the absorption spectrum. Benzyl phenanthroimidazole (5) does not exhibit the photo-enolization due to absence of o-hydroxyl group. Solvatochromism, time resolved photoluminescence measurement and ionic interactions studies of 3–5 are examined in semi-aqueous medium through UV–vis and fluorescence spectroscopy. Fluorescent probe 3 exhibits fluorescence “turn Off” and “turn On” responses with acetate ions in semi-aqueous medium by tuning the excitation wavelength.

Method for preparing 2-aryl-1H-phenanthro (9,10-d) imidazole derivative in catalyzed mode

The invention discloses a method for preparing a 2-aryl-1H-phenanthro (9,10-d) imidazole derivative in a catalyzed mode, and belongs to the technical field of ionic liquid catalysis. In a preparation reaction, the molar ratio of 9,10-phenanthrenequinone to aromatic aldehyde to ammonium acetate is 1:1:3-5, the molar weight of a non-imidazolyl acidic ionic liquid catalyst accounts for 4-6% that of 9,10-phenanthrenequinone, the volume dose of reaction solvent water in units of milliliter is 5-8 times the molar weight of 9,10-phenanthrenequinone in units of millimole, the time for a reflux reaction is 14-30 min, diethyl ether is used for extraction after the reaction is finished, anhydrous magnesium sulfate is added into extract liquor for drying, suction filtration is carried out, and after rotary evaporation concentration is carried out, filtrate is recrystallized with ethyl acetate to obtain the 2-aryl-1H-phenanthro (9,10-d) imidazole derivative. The method has the advantages that the catalyst is good in biodegradability and high in raw material use ratio, the whole preparation process is easy and convenient to operate and the like, and the method can be industrially applied on a large scale conveniently.

An ESIPT fluorescent dye based on HBI with high quantum yield and large Stokes shift for selective detection of Cys

We report 3-(4,5-diphenyl-1H-imidazol-2-yl)naphthalen-2-ol (DPIN) as an interesting luminescent material displaying ESIPT with a large Stokes shift of ～180 nm even in protic/polar solvents. Stable homo-dispersed nanoparticles formed by inter- and intramol

Synthesis, characterization and optical properties of aryl and diaryl substituted phenanthroimidazoles

This article presents a facile synthesis of novel class of blue-green fluorescent phenanthroimidazoles and report on their optical, electrochemical, and thermal properties. Detailed photophysical and quantum chemical studies with a series of hydroxy-, met

Schiff base transition metal complex catalyzed one-pot synthesis of 2-aryl-1H-phenanthro[9,10-d]imidazoles

A rapid, efficient, and novel methodology for the synthesis of 2-aryl-1H-phenanthro[9,10-d]imidazole derivatives, catalyzed by bis[N-(3,5-dicumylsalicylidene)-2',6'- fluoroanilinato]zirconium(IV) dichloride under ultrasonic irradiation at room temperature, is reported. A range of substituted imidazoles was synthesized in excellent yields from one-pot reaction of aromatic aldehydes, 9,10-phenanthrenequinone, and ammonium acetate. The remarkable features of this new procedure are introducing a new one-pot method for synthesis of 2-aryl-1H-phenanthro[9,10-d]imidazoles, high conversion, short reaction time, and simple experimental and workup procedure. Copyright Taylor & Francis Group, LLC.