24309-36-2

Basic information

• Product Name: 7-Ethyl Adenine
• Synonyms: 7-Ethyl Adenine;7-ethylpurin-6-amine
• CAS NO: 24309-36-2
• Molecular Formula: C7H9N5
• Molecular Weight: 163.17986
• Product Categories: Amines, Aromatics, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemical
• Mol File: 24309-36-2.mol

Chemical Properties

• Melting Point: 237-240 °C
• Boiling Point: 382.2°C at 760 mmHg
• Flash Point: 185°C
• Appearance: /
• Density: 1.49g/cm³
• Vapor Pressure: 4.79E-06mmHg at 25°C
• Refractive Index: 1.753
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 4.71±0.30(Predicted)
• CAS DataBase Reference: 7-Ethyl Adenine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Ethyl Adenine(24309-36-2)
• EPA Substance Registry System: 7-Ethyl Adenine(24309-36-2)

Safety Data

• Hazardous Substances Data: 24309-36-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
7-Ethyl Adenine is used as a precursor for the preparation of alkyl bromoadenine derivatives, which serve as A2A and A2B receptor antagonists. These antagonists have potential applications in the development of drugs targeting various diseases and conditions.
Used in Microbial Determination:
7-Ethyl Adenine is utilized in the microbial determination of niacin, an essential nutrient for the human body. This application aids in understanding the role of niacin in various biological processes and its deficiency in certain conditions.
Used in Research on Heredity:
7-Ethyl Adenine plays a crucial role in research related to heredity, as it is involved in the study of genetic information and its transmission across generations. This research contributes to the understanding of genetic disorders and the development of potential treatments.
Used in Research on Virus Diseases:
In the field of virology, 7-Ethyl Adenine is used for studying virus diseases and their impact on human health. This research can lead to the development of antiviral drugs and vaccines to combat viral infections.
Used in Cancer Research:
7-Ethyl Adenine is employed in cancer research to study the mechanisms underlying tumor growth and progression. Understanding these mechanisms can help in the development of targeted therapies and improve the treatment of various types of cancer.

InChI:InChI=1/C7H9N5/c1-2-12-4-11-7-5(12)6(8)9-3-10-7/h3-4H,2H2,1H3,(H2,8,9,10)

Upstream product

• 75-03-6 ethyl iodide 
• 73-24-5 7H-purin-6-ylamine 

Relevant articles and documents

Heterocyclic Ambident Nucleophiles. III* The Alkylation of Sodium Adenide

The alkylation of sodium adenide in HCONMe2 (30 deg) with various alkylating agents was analysed by 1H n.m.r. spectroscopy.Widely varying N3:N7:N9 alkylation patterns were observed, depending on the alkylating agent.These patterns are interpreted in terms of the electrostatic, thermodynamic and steric factors involved in the different SN2 transition states appropriate to each alkylating agent.Hydrogen bonding association between the 6-amino group and certain carbonyl containing alkylating agents is proposed to explain the enhancedN7-alkylation in some cases.Support for this latter proposal was obtain from a comparison of the adenine alkylation results with the corresponding alkylation patterns of 6-pivaloylamino- and 6-chloro-purine.