2432-44-2Relevant academic research and scientific papers
A convenient one-pot synthesis of thiol esters from disulfides using a Zn/AlCl3 system
Movassagh,Lakouraj,Fadaei
, p. 22 - 23 (2007/10/03)
A novel synthetic procedure for the direct preparation of thiol esters from various disulfides and symmetrical anhydrides using a Zn/AlCl3 system is described.
Reactions Potentially Related to Coenzyme B12 Dependent Rearrangements: Observations on the Radical -Acyl and -Thiol Ester Migrations
Best, Wayne M.,Cook, Anthony P. F.,Russell, James J.,Widdowson, David A.
, p. 1139 - 1144 (2007/10/02)
Reaction of 2-iodomethyl-2-methyl-3-oxo esters with tributyltin radicals, generated photochemically from hexabutylditin or tributyltin hydride in cyclohexane, or benzene-acetonitrile, resulted in a -acyl migration in 10-63percent yields dependent on the source of tin radical and substrate used.Radical migration was confirmed by the use of tributyltin deuteride.Thiol ester group migration was not observed.A new, highly efficient method for thiol ester synthesis is described.
The Reductive Acylation of Organic Disulfides with Aldehydes under Photochemical and Radical Conditions
Takagi, Makoto,Goto, Setsuo,Tazaki, Masato,Matsuda, Tsutomu
, p. 1982 - 1987 (2007/10/02)
The irradiation of organic disulfides in aldehyde solvents resulted in the reductive fission of the S-S linkage, giving an equimolar mixture of the corresponding thiol and thiol acylate in a good yield.The cyclic disulfides gave mono S-acylated dithiols.The reaction proceeded by means of the photo-initiated radical chain mechanism, and AIBN (azobisisobutyronitrile) effected the same reaction under thermal conditions.
