24341-71-7

Upstream product

• 24341-74-0 thiophene-2-carboxylic acid 2-benzoyl-4-chloro-anilide 
• 98-03-3 thiophene-2-carbaldehyde 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 84571-01-7 6-Chloro-4-phenyl-2-thiophen-2-yl-1,2,3,4-tetrahydro-quinazoline 

Relevant academic research and scientific papers

Efficient One-Pot Synthesis of Quinazoline and Benzopyrano[2,3-d]pyrimidine Derivatives Catalyzed by N-Bromosulfonamides

N,N,N',N'-tetrabromobenzene-1,3-disulfonamide and poly(N,N’-dibromo-N-ethyl-benzene-1,3-disulfonamide) were used as efficient catalysts for one-pot synthesis of new quinazoline derivatives from various aldehydes, 2-amino-benzophenone, and ammonium acetate

Pentafluorophenylammonium triflate as a suitable and effective metal-free catalyst for the synthesis of quinazoline derivatives via one-pot multicomponent method

A simple and facile synthesis of highly functionalized quinazoline derivatives has been successfully developed by treatment of aldehydes, ammonium acetate, and 2-aminoaryl ketones or isatoic anhydride under reflux conditions in the presence of a pentafluorophenylammonium triflate (PFPAT) organocatalyst. These catalytic condensation reactions represent green chemical processes, while the PFPAT organocatalyst is air-stable, cost-effective, easy to handle, and easily removed from the reaction mixtures.