243467-32-5

Upstream product

• 2387-20-4 1-(2-chloroethyl)imidazolidin-2-one 
• 243467-24-5 1-(4-fluorophenyl)-5-[(2-methyl-2H-1,2,3,4-tetrazol-5-yl)methyl]-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole 
• 243467-59-6 1-(4-fluorophenyl)-5-(hydroxymethyl)-1H-indole 
• 138900-18-2 1-(4-fluorophenyl)-5-cyano-1H-indole 
• 41979-39-9 4-piperidone hydrochloride 
• 243467-65-4 1-(4-fluorophenyl)-5-[(2H-1,2,3,4-tetrazol-5-yl)methyl]-1H-indole 
• 243467-61-0 1-(4-fluorophenyl)-5-[(2-methyl-2H-1,2,3,4-tetrazol-5-yl)methyl]-1H-indole 
• 243467-60-9 (1-(4-fluorophenyl)-1H-indole-5-carboxylic acid) 
• 243467-63-2 5-chloromethyl-1-(4-fluorophenyl)-1H-indole 
• 243467-64-3 5-(cyanomethyl)-1-(4-fluorophenyl)-1H-indole 

Relevant academic research and scientific papers

5-heteroaryl substituted indoles

The present invention relates to compounds having general formula (I) as defined herein, or a pharmaceutically acceptable acid addition salt thereof. The compounds are selective α1-adrenoceptor ligands.

Synthesis and structure-affinity relationship investigations of 5-aminomethyl and 5-carbamoyl analogues of the antipsychotic sertindole. A new class of selective α1 adrenoceptor antagonists

A new class of selective α1 adrenoceptor antagonists derived from the antipsychotic drug sertindole is described. The most potent and selective compound 1-(2-{4-[5-aminomethyl-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl} ethyl)-2-imidazolid