243467-65-4 Usage
Molecular structure
The compound has an indole ring, a 4-fluorophenyl group, and a 1H-tetrazol-5-ylmethyl side chain.
Biological activity
The indole ring and tetrazole side chain are known for their interactions with certain receptors in the body.
Therapeutic potential
The compound has been investigated for its potential as a drug candidate in various areas such as cardiovascular, neurological, and metabolic disorders.
Chemical synthesis
The compound's structure makes it a valuable building block for the synthesis of novel drug molecules.
Common use
The compound is commonly used in pharmaceutical research and drug development due to its potential therapeutic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 243467-65-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,3,4,6 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 243467-65:
(8*2)+(7*4)+(6*3)+(5*4)+(4*6)+(3*7)+(2*6)+(1*5)=144
144 % 10 = 4
So 243467-65-4 is a valid CAS Registry Number.
243467-65-4Relevant academic research and scientific papers
Synthesis and structure-affinity relationship investigations of 5-aminomethyl and 5-carbamoyl analogues of the antipsychotic sertindole. A new class of selective α1 adrenoceptor antagonists
Balle, Thomas,Perregaard, Jens,Larsen, Anna K.,Ramirez, Martha Teresa,Soby, Karina Krojer,Liljefors, Tommy,Andersen, Kim
, p. 1065 - 1078 (2007/10/03)
A new class of selective α1 adrenoceptor antagonists derived from the antipsychotic drug sertindole is described. The most potent and selective compound 1-(2-{4-[5-aminomethyl-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl} ethyl)-2-imidazolid
5-heteroaryl substituted indoles
-
, (2008/06/13)
The present invention relates to compounds having general formula (I) as defined herein, or a pharmaceutically acceptable acid addition salt thereof. The compounds are selective α1-adrenoceptor ligands.
