139718-48-2

Upstream product

• 3236-56-4 dipercarbonate de O,O-t-butyle 
• 139718-50-6 5-bromo-1-(4-fluorophenyl)-3-(4-piperidyl)-1H-indole 
• 24424-99-5 di-tert-butyl dicarbonate 
• 139718-49-3 5-cyano-1-(4-fluorophenyl)-3-(4-piperidyl)-1H-indole 
• 489468-61-3 5-bromo-1-(4-fluorophenyl)-3-(1,2,3,6-tetrahydro-4-pyridyl)-1H-indole 
• 138900-24-0 1-(4-fluorophenyl)-5-bromo-1H-indole 
• 352-34-1 4-fluoro-1-iodobenzene 
• 10075-50-0 5-bromo-1H-indole 

Downstream Products

• 243467-66-5 4-[1-(4-fluorophenyl)-5-(2-methyl-tetrazol-5-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 
• 489468-63-5 4-[1-(4-fluorophenyl)-5-(1-methyl-tetrazol-5-yl)-1H-indol-3-yl]piperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

5-heteroaryl substituted indoles

The present invention relates to compounds having general formula (I) as defined herein, or a pharmaceutically acceptable acid addition salt thereof. The compounds are selective α1-adrenoceptor ligands.

Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective α1 adrenoceptor antagonists

A new class of 5-heteroaryl-substituted 1-(4-fluorophenyl)-3-(4-piperidinyl)-1H-indoles as highly selective and potentially CNS-active α1-adrenoceptor antagonists is described. The compounds are derived from the antipsychotic sertindole. The st

PIPERIDYL-SUBSTITUTED INDOLES FOR TREATING ANXIETY

A method for treating anxiety in mammals comprising administering in an effective amount to said mammal an 1-aryl-3-(4-piperidyl)-indole derivative having the general formula: STR1 wherein R 1 is H, F, Cl, Br, methyl, methoxy or cyano; and R 3 is H or met

Method for treating memory impairment

A method for treating memory impairment is disclosed. The method comprises administering a therapeutically effective amount of a compound having the formula: STR1 or a pharmaceutically acceptable acid addition salt or prodrug therefor to a patient.

Treatment of addiction to drugs and substances of abuse

1-Aryl-3-(4-1piperidyl)-indole derivatives having general formula (I), STR1 wherein R 1 is hydrogen, halogen, alkyl, alkoxy, hydroxy, cyano, nitro, alkylthio, trifluoromethyl, trifluoromethylthio, alkylsulfonyl, amino, alkylamino or dialkylaminio; R is op